Evidence map›Paper›PMID 41378456›Full record

ArticleJournal of the American Heart Association2025

Nationwide Trends in Incidence of Stroke and Transient Ischemic Attack in Younger and Older Adults in Norway 2001 to 2021.

Elisabeth Kvalvaag, Vidar Hjellvik, Lars Kjerpeseth, Jannicke Igland, Hanne Ellekjær, Gerhard Sulo, Mariam Anjum, Kjersti S Rabanal, Trygve Berge, Inger Ariansen

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Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Elisabeth KvalvaagDepartment of Chronic Diseases Norwegian Institute of Public Health Oslo Norway.ORCID 0009-0009-8826-7984
Vidar HjellvikDepartment of Chronic Diseases Norwegian Institute of Public Health Oslo Norway.ORCID 0000-0002-2379-9906
Lars KjerpesethDepartment of Chronic Diseases Norwegian Institute of Public Health Oslo Norway.
Jannicke IglandDepartment of Global Public Health and Primary Care University of Bergen Norway.
Hanne EllekjærDepartment of Neuroscience Norwegian University of Science and Technology Trondheim Norway.
Gerhard SuloDepartment of Global Public Health and Primary Care University of Bergen Norway.ORCID 0000-0002-1247-1577
Mariam AnjumDepartment of Chronic Diseases Norwegian Institute of Public Health Oslo Norway.
Kjersti S RabanalDepartment of Public Health University of Stavanger Norway.
Trygve BergeDepartment of Medical Research Bærum Hospital, Vestre Viken Hospital Trust Gjettum Norway.ORCID 0000-0002-7681-8621
Inger AriansenDepartment of Chronic Diseases Norwegian Institute of Public Health Oslo Norway.ORCID 0000-0001-8529-4826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is conflicting evidence on the time trends of stroke incidence in younger adults. We aimed to explore time trends in the incidence of stroke, stroke subtypes, and transient ischemic attack in different age groups in Norway the past 2 decades.

methodsIn this nationwide registry-based cohort study, we identified incident stroke cases from hospitalizations with stroke (ischemic stroke, intracerebral hemorrhage and unspecified stroke), transient ischemic attack, or out-of-hospital deaths due to stroke. Included individuals were aged ≥15 years with no prior hospitalization for stroke during the past 7 years. Incidence per 100 000 population was age-standardized and presented by year, sex, and age group. Average annual percentage changes in incidence were estimated using weighted log-linear regression.

resultsFrom 2001 to 2021, we identified 229 857 incident total stroke cases (49.2% women) among 5 691 495 individuals in the Norwegian adult population. Incidence per 100 000 population decreased over time for all stroke subtypes in both men and women. However, the incidence of ischemic stroke for men aged <35 years increased annually by 1.6% (95% CI, 0.3-2.8). For intracerebral hemorrhage, the incidence was stable in younger men and women and the oldest women. For transient ischemic attack, both sexes experienced a sharp rise in the incidence until 2012, followed by a substantial decrease.

conclusionsTotal stroke incidence declined from 2001 to 2021. However, less favorable time trends were observed in younger age groups, with a worrisome increase in ischemic stroke incidence among men aged 15 to 34 years. These trends are concerning and need further investigation.

Indexed as

Ischemic Attack, TransientStrokeAdolescentAdultAgedAged, 80 and overAge DistributionAge FactorsFemaleHumansIncidenceMaleMiddle AgedNorwayRegistriesTime FactorsincidencestrokeTIAtime trendtransient ischemic attack

Identifiers

PMID41378456
PMCPMC12826924

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