Evidence map›Paper›PMID 41378257›Full record

ArticleFrontiers in veterinary science2025

Mechanism of exogenous enzymes participation in the regulation of digestion and metabolism in model chickens.

Vladimir Vertiprakhov, Bayarma S Dashieva, Alexei M Grigoriev, Veronika D Ashikhmina

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vladimir VertiprakhovMoscow Timiryazev Agricultural Academy, Moscow, Russia.
Bayarma S DashievaMoscow Timiryazev Agricultural Academy, Moscow, Russia.
Alexei M GrigorievMoscow Timiryazev Agricultural Academy, Moscow, Russia.
Veronika D AshikhminaMoscow Timiryazev Agricultural Academy, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experiments were performed on fistulas with duodenal cannula, which can reflect the function of the pancreas and are a model for studying digestion and metabolism when using biologically active additives. The aim of this work is to study the effect of different doses of enzyme preparation prepared from pig pancreas tissue on duodenal enzyme activity, calcium phosphorus, blood biochemical status and productivity in laying hens using fistula technology. The enzyme preparation prepared from pig pancreatic gland tissue was standardized for trypsin activity, which was 187 units/g. The results showed that a dose of 0.01% of the enzyme preparation from the feed weight stimulated metabolism and influenced productive metabolism, increasing egg production by 25.0% compared to the control group, increasing the dose of the preparation led to an increase in trypsin activity in the duodenum, but critically influenced egg formation, reducing its mass by 5.8% and increasing egg laying capacity by 12.5% against the control. Consequently, the use of enzymes should be controlled from the side of mineral metabolism, which can be disturbed at high doses of the drug.

Indexed as

chickensduodenal chymeenzyme preparationfistulated birdstrypsin

Identifiers

PMID41378257
PMCPMC12685682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.