Evidence map›Paper›PMID 41378162›Full record

ArticleeNeurologicalSci2025

Longitudinal trends in stroke risk factors and mortality over 20 years from a central stroke referral center in Pakistan using clinically digitized data.

Namrah Aziz, Shafaq Saleem, Saadia Sattar, Sara Khan, Mohammad Wasay, Saad Shafqat, Dureshawar Kanwar, Sarwar Siddiqui, Sajid Hameed, Mushyada Ali and 2 more

Abstract read
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Article in eNeurologicalSci, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Namrah AzizDeans Clinical Research Fellow, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Shafaq SaleemInstructor Research, Fogarty Fellow, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Saadia SattarSenior Instructor, Department of medicine, Aga Khan University Hospital, Karachi, Pakistan.
Sara KhanSection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Mohammad WasaySection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Saad ShafqatSection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Dureshawar KanwarSection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Sarwar SiddiquiSection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Sajid HameedSection of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Mushyada AliDepartment Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Zainab SamadDepartment Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Ayeesha Kamran KamalStroke Service, Section of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited data exists on long-term stroke trends in low- and middle-income countries, including Pakistan, despite its growing burden. Understanding these trends is crucial for informing healthcare strategies and public health interventions. This study examines 20-year trends in stroke characteristics, risk factors, and mortality at a tertiary care center in Pakistan. Methods: In this retrospective study, a secondary analysis was conducted using clinically digitized records from the Aga Khan University Hospital. Patients aged ≥18 years, admitted with stroke, and discharged between January 1, 1999, and December 31, 2018, were included. Stroke subtypes were classified using Results: The final cohort included 12,837 patients: 71.4 % ischemic stroke, 21.2 % ICH, and 7.4 % TIA. The median age was 62 years (IQR: 52-70). Stroke admissions rose over time ( Conclusion: Stroke patterns are shifting toward younger age and greater risk factor clustering, though in-hospital mortality has declined. Continued surveillance and targeted interventions are essential.

Indexed as

MortalityRisk factorsStrokeTemporal trends

Identifiers

PMID41378162
PMCPMC12686703

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