Evidence map›Paper›PMID 41378160›Full record

ArticleHemaSphere2025

Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early-life

Lucca L M Derks, Konradin F Müskens, Markus J van Roosmalen, Aniek O de Graaf, Nina Epskamp, Laurianne Trabut, Rico Hagelaar, Joop H Jansen, Caroline A Lindemans, Maaike G J M van Bergen and 2 more

Erratum issuedAbstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Lucca L M DerksPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Konradin F MüskensPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Markus J van RoosmalenPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Aniek O de GraafLaboratory of Hematology Radboud University Medical Center Nijmegen The Netherlands.
Nina EpskampPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Laurianne TrabutPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Rico HagelaarPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Joop H JansenLaboratory of Hematology Radboud University Medical Center Nijmegen The Netherlands.
Caroline A LindemansPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Maaike G J M van BergenLaboratory of Hematology Radboud University Medical Center Nijmegen The Netherlands.
Ruben van BoxtelPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.
Mirjam E BelderbosPrincess Máxima Center for Pediatric Oncology Utrecht The Netherlands.ORCID https://orcid.org/0000-0002-6164-2918

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clonal hematopoiesis (CH), a prevalent and premalignant state in the elderly, has been detected in young individuals under selective pressures such as hematopoietic cell transplantation (HCT). However, the origin of CH and mutational processes underlying CH driver mutations in young blood systems remain unclear. Here, we used genome-wide somatic mutation profiles to retrospectively trace the origin of

Identifiers

PMID41378160
PMCPMC12686829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.