ArticleResearch square2025
Overcoming Immune Exclusion in a Murine Model of Cirrhotic Hepatocellular Carcinoma via Cryoablation: Insights from Molecular Extracellular pH Imaging.
Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Solid tumors, including hepatocellular carcinoma (HCC), arises most often in cirrhotic livers, where immune exclusion and metabolic reprogramming drive extracellular acidosis (the "Warburg effect") and create an immunosuppressive tumor microenvironment (TME). This study applied a non-invasive MR Spectroscopic Imaging method called Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) to quantify extracellular pH (pH
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.