ArticleFrontiers in endocrinology2025
Correlation of body compositions and bone mineral density in postmenopausal women with different body mass index.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Independent Associations of Appendicular Skeletal Muscle Mass Index and Waist Circumference with Site-Specific Bone Mineral Density in Postmenopausal Women: A Real-World Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Association between weight-to-waist ratio and total bone mineral density in US adults: A cross-sectional study of the National Health and Nutrition Examination Survey 2011-2018.The Journal of international medical research · 2026Article
- TyG-BMI as a Marker of Metabolic Status and Its Association with Bone Quality and Mineral Metabolism: A Sex-Specific Analysis.Journal of clinical medicine · 2026Article
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Authors and funding
8 authors.
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Abstract
Background: The association between obesity and bone mineral density (BMD) is controversial. Body composition parameters have been found to be strongly correlated with BMD. Body mass index(BMI)cannot distinguish between muscle and adipose tissue. The objective of this study was to evaluate the association of body composition with BMD in postmenopausal women with different BMI. Methods: 356 postmenopausal women were divided into three groups(normal weight, overweight and obesity)according to BMI. BMD and body composition components were obtained by Dual-energy X-ray Absorptiometry. The collected data served as the training set for model development, while datasets from the NHANES database were utilized as a validation set to assess model performance. Multivariable linear regression models evaluated associations between parameters of body composition and BMD in different BMI participants. Results: In univariate analysis, BMI, total fat mass, soft lean mass (SLM), appendicular skeletal muscle mass, relative skeletal muscle index (RSMI) were positively correlated with BMD at all sites (r = 0.181-0.388, all Conclusions: The study demonstrates that the effect of body compositions on BMD varies by BMI classification and site-specific differences in postmenopausal women. Increased abdominal fat may confer a potential benefit for BMD in non-obese women with relative metabolic health. Conversely, optimizing body composition by reducing body fat and increasing muscle mass remains crucial for skeletal health in postmenopausal women.
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