ArticleFrontiers in endocrinology2025
Relationship between thyroid nodules and iodine nutritional status, thyroglobulin (Tg), and other influencing factors: a 1:1 matched case-control study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: An increasing trend in the prevalence of thyroid nodules has highlighted whether thyroid nodules are related to the level of iodine nutrition. Methods: This 1:1 matched case-control study was conducted to investigate whether thyroid nodules are related to the level of iodine nutrition. The residents who had lived there for more than 5 years with thyroid nodules composed the case group. All the subjects completed questionnaires, and blood and urine samples were collected. Results: The MUI of the case group in areas with more than adequate iodine intake was lower than that of the control group ( Conclusions: In areas with more than adequate iodine intake, a slight increase in urinary iodine may be associated with a lower risk of thyroid nodules. A history of thyroid disorders and increased Tg and TgAb levels are risk factors for thyroid nodules. Tg level detection has certain diagnostic value in distinguishing thyroid nodules.
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