ArticleFrontiers in cardiovascular medicine2025
Association between the age-to-serum albumin ratio and all-cause mortality in patients with acute myocardial infarction: a retrospective cohort study.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Establishment and validation of a machine learning-based predictive model for in-hospital mortality risk in acute myocardial infarction patients complicated with diabetes mellitus.Frontiers in cardiovascular medicine · 2026Article
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4 authors.
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Abstract
Background: Acute myocardial infarction (AMI) remains a predominant cause of cardiovascular death, necessitating accurate risk stratification. Existing risk scores like the ACEF (Age, Creatinine, Ejection Fraction) score and GRACE (Global Registry of Acute Coronary Events) score have limitations in complexity and subjectivity. This study aimed to investigate the novel age-to-serum albumin ratio (A2A Index) as a simple, objective predictive marker for all-cause mortality in AMI patients. Methods: The A2A Index was retrospectively calculated by dividing age by serum albumin in 1,007 consecutively enrolled AMI patients with 4-year median follow-up. The association between the A2A Index and all-cause mortality was assessed using Kaplan-Meier survival analysis, Cox regression analysis, and restricted cubic spline. The predictive performance of the A2A Index was compared with the ACEF and GRACE scores. Results: The A2A Index was capable of independently predicting all-cause mortality after multivariable adjustment [hazard ratio (HR) 4.98 per one-unit increase in A2A Index; 95% CI: 3.34-7.43; Conclusion: The A2A Index is a simple and independent predictor of all-cause mortality in AMI patients, superior to GRACE score and comparable to ACEF score, with >1.86 indicating high mortality risk.
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