ArticleGland surgery2025
Thermal ablation for papillary thyroid carcinoma in the isthmus: a systematic review and meta-analysis.
Article in Gland surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Survival outcomes following isthmusectomy versus lobectomy and total thyroidectomy for papillary thyroid carcinoma: A propensity score-matched study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Clinical outcomes of lobectomy versus isthmusectomy for clinically node-negative solitary isthmic papillary thyroid microcarcinoma: a retrospective cohort study.Gland surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Clinical investigations have demonstrated that the potential efficacy and safety of thermal ablation (TA) in treating papillary thyroid carcinoma in the isthmus (PTCI). However, almost all studies were non-randomized controlled trials with small sample sizes. This meta-analysis aims to comprehensively and systematically evaluate its effectiveness. Methods: A systematic search for related studies was conducted in PubMed, EMBASE, and Cochrane Library from the database establishment to Jan 31, 2025. Outcomes including local tumor progression (LTP), postoperative volume, complete disappearance rate (CDR), locoregional recurrence (LRR), distant metastasis (DM) and complication, were evaluated for further analysis. Results: The meta-analysis included 560 unifocal PTCI from seven studies. No LTP was found in all patients. It was found that tumor volume had decreased significantly at 12 and 18 months following TA, in contrast to baseline measurements (P<0.05). The pooled analysis demonstrated an 88.10% CDR for PTCI [95% confidence interval (CI): 66.20-99.87%], with an overall complication incidence of 0.89% (95% CI: 0.13-2.08%). Six patients developed new tumors (0.77%; 95% CI: 0.04-2.06%). Lymph node metastasis (LNM) was documented in a single case (1/468; 95% CI: 0.00-0.56%). During the follow-up period, no patients were found to have DM. Conclusions: This meta-analysis indicated that TA possesses promising efficacy and safety for individuals with PTCI. Multinational, prospective studies are warranted to confirm its generalizability in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.