Evidence map›Paper›PMID 41377719›Full record

ArticleFrontiers in public health2025

Long-term spatial-temporal evolution of hepatitis C burden in eastern China: a retrospective case analysis from Wuxi City.

Huan Ding, Qi Zhang, Shiya Shen, Song Gao, Shipeng Zhang, Zhuping Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huan Ding *Department of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Qi Zhang *Department of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Shiya ShenDepartment of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Song GaoDepartment of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Shipeng ZhangDepartment of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Zhuping XuDepartment of Chronic Infectious Disease Control and Prevention, The Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hepatitis C is an inflammation of the liver caused by the hepatitis C virus (HCV) and represents a major public health challenge. This study aimed to explore the epidemiological characteristics and spatiotemporal distribution of hepatitis C in Wuxi City, a developed and low-epidemic area of eastern China, from 2007 to 2021. Methods: Data were obtained from the Chinese Information System for Disease Control and Prevention, while genotype information was derived from a retrospective survey. Statistical analyses were conducted using SPSS software to identify characteristic differences. Joinpoint regression analysis was applied to examine long-term temporal trends, and the concentration degree was used to quantify seasonal intensity. Kernel density and hotspot analyses were applied to identify spatial distribution patterns and clusters. Results: A total of 4,771 cases were recorded, with an average annual incidence rate of 5.44 per 100,000 population. The incidence was significantly higher in males than in females (odds ratio = 1.49, Conclusion: The incidence of HCV in Wuxi City has increased steadily from 2007 to 2021, with genotypes 1b and 3 being predominant. Spatial clustering was mainly concentrated in urban centers, highlighting the need for targeted prevention and control strategies to support the goal of eliminating HCV as a public health threat by 2030.

Indexed as

Hepatitis CAdolescentAdultAgedChildChinaFemaleGenotypeHepacivirusHumansIncidenceMaleMiddle AgedRetrospective StudiesSeasonsSpatio-Temporal AnalysisChinaepidemiologygenotype distributionhepatitis C viruspublic health surveillancespatiotemporal analysis

Identifiers

PMID41377719
PMCPMC12685834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.