Evidence map›Paper›PMID 41377716›Full record

ArticleFrontiers in public health2025

L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.

Yanqin Li, Qi Gao, Fan Luo, Yuxin Lin, Ruqi Xu, Pingping Li, Yuping Zhang, Jiao Liu, Hongrui Zhan, Licong Su

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In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yanqin Li *Division of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qi Gao *Department of Nephrology, Wuhan Fourth Hospital, Wuhan, Hubei, China.
Fan LuoDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuxin LinDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ruqi XuDivision of Nephrology, People's Hospital of Yangjiang Affiliated to Guangdong Medical University, Yangjiang, China.
Pingping LiDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuping ZhangDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jiao LiuDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Hongrui ZhanDepartment of Rehabilitation, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China.
Licong SuDivision of Nephrology, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have shown that the triglyceride glucose-body mass index (TyG-BMI) is associated with cardiovascular disease, stroke, and cognition. Its relationship with mental health remains underexplored. We aimed to investigate the association between TyG-BMI and mental health in Chinese adults. Methods: This study utilized data from the China Health and Nutrition Survey (CHNS), an ongoing longitudinal cohort. Participants aged ≥45 years who completed at least two survey rounds between 2009 and 2015 were included. The TyG index was calculated as ln [triglycerides (mg/dL) × fasting blood glucose (mg/dL) / 2]. BMI was calculated as weight (kg) divided by height squared (m Results: Among 2,951 participants (47.6% male, median age 56.0 [25th, 75th percentile: 51, 64] years), the median TyG-BMI was 204.3 [25th, 75th percentile: 179.6, 231.8]. Over a median follow-up of 6.0 [2.0, 6.1] years, 1,026 (34.8%) incident was identified poor self-rated mental health. RCS curves indicated an L-shaped association between TyG-BMI and self-rated mental health ( Conclusion: This study revealed an L-shaped association between TyG-BMI and self-rated mental health in mentally healthy, middle-aged and older Chinese individuals. Our findings suggest that TyG-BMI may serve as an effective tool for enhancing the primary prevention of mental health.

Indexed as

Blood GlucoseBody Mass IndexMental HealthTriglyceridesAgedChinaCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedNutrition SurveysSelf ReportBlood GlucoseTriglyceridesCHNSinsulin resistancemental healthprospective cohort studyTyG-BMI

Identifiers

PMID41377716
PMCPMC12685690

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