Evidence map›Paper›PMID 41377706›Full record

ArticleEuropean heart journal. Case reports2025

Iatrogenic mitral chordal rupture induced by microaxial flow pump in acute myocardial infarction complicated by cardiogenic shock-a case report.

Tharusan Thevathasan, Ulf Landmesser, Stephan Jacobs, Carsten Skurk, Andi Rroku

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tharusan ThevathasanDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12203, Germany.ORCID https://orcid.org/0000-0003-4698-4079
Ulf LandmesserDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12203, Germany.
Stephan JacobsDeutsches Zentrum für Herz-Kreislauf-Forschung, Partner Seite Berlin, Potsdamer Str. 58, 10785 Berlin, Germany.
Carsten SkurkDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12203, Germany.ORCID https://orcid.org/0000-0003-4953-601X
Andi RrokuDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12203, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mechanical circulatory support devices, such as microaxial flow pumps (mAFP), are used in the management of cardiogenic shock, particularly in the setting of ST-segment elevation myocardial infarction. While these devices are potentially life-saving, their use is not without risk and might be associated with rare but serious complications, including structural cardiac injury. Case summary: We report the case of a 41-year-old male with known polysubstance abuse who experienced an out-of-hospital cardiac arrest due to ST-segment elevation myocardial infarction. Following successful return of spontaneous circulation and emergent percutaneous coronary intervention, a mAFP was implanted for haemodynamic stabilization. Echocardiographic monitoring initially confirmed correct positioning without evidence of valvular dysfunction. However, on Day 4, imaging revealed entrapment of the mAFP within the mitral valve's subvalvular apparatus. Following careful device explantation, the patient showed new-onset severe mitral regurgitation (MR) due to posterior leaflet chordal rupture. Transoesophageal echocardiography confirmed a flail P3 segment. The presence of severe MR hindered adequate recompensation and complicated the weaning process from ventilatory support. The immediately consulted multidisciplinary Heart Team recommended early surgical intervention. The patient subsequently underwent successful mitral valve repair, resulting in clinical stabilization and eventual discharge to a rehabilitation facility in improved condition. Discussion: This case highlights a potential rare iatrogenic complication of mAFP support and emphasizes the necessity of meticulous echocardiographic surveillance, timely recognition of complications, and guideline-based multidisciplinary decision-making in the management of critically ill patients.

Indexed as

Cardiogenic shockCase reportChordal ruptureMechanical circulatory supportMicroaxial flow pumpMitral regurgitation

Identifiers

PMID41377706
PMCPMC12687143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.