Evidence map›Paper›PMID 41377628›Full record

ReviewCirculation reports2025

Should Sedative Administration Be Recommended as an Antiarrhythmic Therapy to Suppress Ventricular Fibrillation and Ventricular Tachycardia in Patients With Electrical Storm? - A Scoping Review.

Takayuki Kitai, Tetsuma Kawaji, Yukio Hosaka, Mutsuko Sangawa, Hiroki Shiomi, Eiji Hiraoka, Kazuo Sakamoto, Kenichi Iijima, Masashi Yokose, Teruo Noguchi and 7 more

Abstract readReview
In one paragraph

Review in Circulation reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Takayuki KitaiDepartment of Cardiovascular Medicine, Sapporo Cardio Vascular Clinic Hokkaido Japan.
Tetsuma KawajiDepartment of Cardiology, Mitsubishi Kyoto Hospital Kyoto Japan.
Yukio HosakaDepartment of Cardiology, Niigata City General Hospital Niigata Japan.
Mutsuko SangawaDepartment of Cardiology, Takamatsu Red Cross Hospital Kagawa Japan.
Hiroki ShiomiDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine Kyoto Japan.
Eiji HiraokaDepartment of Internal Medicine, Tokyo Bay Urayasu Ichikawa Medical Center Chiba Japan.
Kazuo SakamotoDepartment of Cardiovascular Medicine, Kyushu University Hospital Fukuoka Japan.
Kenichi IijimaDepartment of Cardiovascular Biology and Medicine, Juntendo University Hospital Tokyo Japan.
Masashi YokoseDepartment of Diagnostic and Generalist Medicine, Dokkyo Medical University Tochigi Japan.
Teruo NoguchiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Osaka Japan.
Hiroshi TakahashiDepartment of Cardiology, Steel Memorial Muroran Hospital Hokkaido Japan.
Tetsuya MatobaDepartment of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences Fukuoka Japan.
Migaku KikuchiDepartment of Cardiovascular Medicine, Emergency and Critical Care Center, Dokkyo Medical University Tochigi Japan.
Yoshio TaharaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Osaka Japan.
Hiroshi NonogiPharmaceutical Sciences, University of Shizuoka Shizuoka Japan.
Toshikazu FunazakiKawaguchi Cupola Rehabilitation Hospital Saitama Japan.
Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Arrhythmia Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Electrical storm (ES) is defined as a condition in which ventricular tachycardia (VT) or ventricular fibrillation (VF) episodes requiring electrical shock or implantable cardioverter-defibrillator (ICD) shocks occur ≥3 times within 24 h. It is a life-threatening condition, and treatment options include antiarrhythmic drugs, sedation, circulatory support, and catheter ablation. Sedation is conventionally performed for repeated electrical shocks; however, evidence for its effectiveness in ES suppression remains limited. This scoping review aimed to assess whether the use of sedatives is beneficial for ES suppression. Methods and Results: This scoping review followed the PRISMA extension for scoping reviews (PRISMA-ScR) guidelines. Three online databases were searched to identify studies published from the inception of each database until September 18, 2024. To date, no randomized or quasi-randomized controlled trials or observational analytical studies have met the inclusion criteria for the use of sedation in patients with ES. Conclusions: This scoping review underscores the need for high-quality studies to enhance the level of evidence and bridge knowledge gaps, ultimately aiming to shift the care paradigm for patients with ES.

Indexed as

Adrenergic arrhythmia suppressionDeep sedation as a therapeutic bridgeElectrical storm

Identifiers

PMID41377628
PMCPMC12688421

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.