Evidence map›Paper›PMID 41377510›Full record

ArticlebioRxiv : the preprint server for biology2025

Widespread sex-biased gene expression reflects female-biased longevity in a species with environmental sex determination.

Samantha L Bock, Luke A Hoekstra, Kelsi Hagerty, Robert E Schmidt, Jessica Judson, Maxwell Adorsoo, Ritambhara Singh, Fredric J Janzen, Anne M Bronikowski

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha L BockW. K. Kellogg Biological Station, Michigan State University, Hickory Corners, MI, USA.
Luke A HoekstraDepartment of Ecology, Evolution, & Organismal Biology, Iowa State University, Ames, IA, USA.
Kelsi HagertyDepartment of Ecology, Evolution, & Organismal Biology, Iowa State University, Ames, IA, USA.
Robert E SchmidtDepartment of Ecology, Evolution, & Organismal Biology, Iowa State University, Ames, IA, USA.
Jessica JudsonDepartment of Ecology, Evolution, & Organismal Biology, Iowa State University, Ames, IA, USA.
Maxwell AdorsooCenter for Computational Molecular Biology, Brown University, Providence, RI, USA.
Ritambhara SinghCenter for Computational Molecular Biology, Brown University, Providence, RI, USA.
Fredric J JanzenW. K. Kellogg Biological Station, Michigan State University, Hickory Corners, MI, USA.
Anne M BronikowskiW. K. Kellogg Biological Station, Michigan State University, Hickory Corners, MI, USA.

Funding

Biodemography and senescence in long-lived painted turtlesR01AG049416 · NIA · IOWA STATE UNIVERSITY · PI BRONIKOWSKI, ANNE · 2015 to 2019
$1.1M
NIA NIH HHS R01 AG049416
6 · The paper itself

Abstract

Sexes frequently differ in life history traits including body size, lifespan, and age at sexual maturity. Aging, the progressive decline in physiological function and cellular resilience over time, is a central process contributing to sex-specific life histories, yet the mechanisms driving sex differences in aging remain largely unresolved. Long-term mark-recapture efforts revealed a striking pattern of female-biased longevity in the painted turtle (

Indexed as

agingenvironmental sex determinationmachine learningtranscriptome

Identifiers

PMID41377510
PMCPMC12687789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.