Evidence map›Paper›PMID 41377213›Full record

ArticleAnnals of medicine and surgery (2012)2025

CAD/CAM-guided vascularized fibula graft for anterior maxillary reconstruction: a case report.

Ziad Albash, Zaderenko Igor Alexandrovich, Hassan Alsayed Hachem, Tereschuk Sergei Vasilevich, Saltykov Egor Michaylovich, Ushenko Ilya Aleksandrovich

Abstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ziad AlbashOral and Maxillofacial Surgery Department, Faculty of Dentistry, Latakia University, Latakia, Syia.ORCID https://orcid.org/0000-0003-2799-970X
Zaderenko Igor AlexandrovichN.N Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, Moscow, Russia.
Hassan Alsayed HachemOral and Maxillofacial Surgery Department, Peoples' Friendship University of Russia, Moscow, Russia.
Tereschuk Sergei VasilevichMedical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko, Moscow, Russia.
Saltykov Egor MichaylovichOral and Maxillofacial Surgery Department, Peoples' Friendship University of Russia, Moscow, Russia.
Ushenko Ilya AleksandrovichOral and Maxillofacial Surgery Department, Peoples' Friendship University of Russia, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: The reconstruction of large anterior maxillary defects poses a significant challenge due to the complex three-dimensional anatomy and functional demands of the midface. While autogenous bone grafts are the gold standard, vascularized free flaps, particularly the fibula, offer superior outcomes for large defects. This case report highlights the application of computer-aided design and computer-aided manufacturing (CAD/CAM) technology to enhance the precision and predictability of such reconstructions. Case presentation: A 22-year-old male presented with a substantial anterior maxillary defect following resection for ameloblastic carcinoma. The reconstruction was performed using a virtual surgical plan to guide the harvest and inset of a vascularized fibula osteocutaneous flap. Pre-bent patient-specific plates and 3D-printed surgical guides were utilized. The procedure was successful, with uneventful healing. Five months post-reconstruction, four dental implants were placed into the fibula graft using a guided surgical protocol, achieving good primary stability. Subsequent prosthetic rehabilitation resulted in the successful restoration of function and aesthetics. Clinical discussion: This case illustrates that a CAD/CAM-guided approach allows for the precise translation of a virtual plan to the operating room, ensuring optimal graft positioning and contour. The integration of a vascularized fibula flap provided a viable bony foundation for endosseous implants, enabling definitive prosthetic rehabilitation. The digital workflow streamlines the surgical process, reduces intraoperative unpredictability, and facilitates a prosthetic-driven treatment plan from the outset. Conclusions: CAD/CAM-guided vascularized fibula graft reconstruction is a highly effective method for managing complex maxillary defects. The technology enables accurate anatomical restoration and creates ideal conditions for dental implant placement, ultimately leading to successful functional and aesthetic rehabilitation. This approach underscores the critical importance of interdisciplinary collaboration and advanced digital planning in modern maxillofacial reconstruction.

Indexed as

bone augmentationCAD/CAMdental implantsmaxillary reconstructionvascularized fibula graftvirtual surgical planning

Identifiers

PMID41377213
PMCPMC12689001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.