ArticleRSC advances2025
Synthesis, characterization, and anticancer activity of tuna bone gelatin peptide-stabilized selenium nanowires.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Organic selenium shows promise in cancer treatment due to its antioxidant properties, however, challenges like toxicity and instability hinder its efficacy. Herein, we aim to develop stable and less toxic selenium-chelated tuna bone gelatin peptides (TBGP@Se). TBGPs were extracted from tuna bones and chelated with selenium through a redox reaction. The resulting TBGP@Se was characterized to assess amino acids sequences, morphology of TBGP@Se, particle size distribution. Antiproliferation activity was evaluated using A549 and HT-29 cell lines. Our TBGP@Se was rich in glycine, proline, and alanine which aided stable Se chelation. Electron micrography confirmed gelatin concentrations (5 mg mL
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