Evidence map›Paper›PMID 41377131›Full record

ArticleJournal of biomedical physics & engineering2025

Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models.

Reza Mahmoudi, Saied Karbalay-Doust, Ehsan Masoudi, Mehrzad Jafari-Barmak, Amir Ghanbri, Mohsen Nikseresht, Seyed Mohammad Javad Mortazavi, Seyed Alireza Mortazavi

Abstract read
In one paragraph

Article in Journal of biomedical physics & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza MahmoudiCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Saied Karbalay-DoustAnatomy Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Ehsan MasoudiStudent Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran.
Mehrzad Jafari-BarmakCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Amir GhanbriCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Mohsen NiksereshtCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Seyed Mohammad Javad MortazaviIonizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Alireza MortazaviMVLS College, The University of Glasgow, Glasgow, Scotland, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Radiofrequency Electromagnetic Fields (RF-EMF) have raised concerns due to their potential adverse effects on reproductive health. However, emerging evidence indicates that exposure to low-level RF-EMF may induce adaptive responses, rendering cells or organisms more resilient to subsequent stressors. Objective: To investigate whether exposure to 2.45 GHz Wi-Fi radiation could mitigate heat-induced damage in the reproductive system of male rats. Material and Methods: In this factorial experimental study, 32 adult male Wistar rats were divided into four groups: control, RF-EMF alone, heat stress alone, and RF-EMF combined with heat stress. Rats in the RF-EMF group were exposed to RF-EMF for 2 hours daily over 52 days, while those in the heat group experienced 10 minutes of heat stress per day over the same period. The 'RF-EMF + heat' group received both RF-EMF and heat exposure. After 52 days, the testes and sperm parameters were assessed. Results: Animals exposed to 'RF-EMF + heat' combined with heat showed significant improvements in testis volume, tubular epithelium, interstitium, cell counts, sperm quality, and Leydig cells compared to those exposed to heat alone ( Conclusion: As far as we know, this is the first study to explore the potential protective effects of RF-EMF exposure against heat-induced structural abnormalities in the testes of male rats. Our findings suggest that RF-EMF exposure may mitigate heat-induced damage, possibly through the induction of adaptive responses. These results have implications for various fields, including reproductive biology, environmental health, and occupational safety, highlighting the need for further research to elucidate the underlying mechanisms.

Indexed as

EMFHyperthermiaRadiofrequencyRatsSpermTestisWi-Fi

Identifiers

PMID41377131
PMCPMC12686669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.