ArticleJournal of thoracic disease2025
Association between early-life respiratory syncytial virus infection and the risk of asthma: a meta-analysis.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Systemic immune programming in the life course of childhood asthma: a new perspective on monocyte pre-activation and trained immunity.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections (LRTIs) in early childhood, yet its long-term impact on asthma development remains uncertain. This meta-analysis aims to quantify the association between early-life RSV-LRTI and the subsequent risk of asthma. Methods: A systematic search of PubMed, Embase, and Web of Science was conducted. Observational studies comparing asthma incidence between children with early-life RSV-LRTI (before 3 years of age) and those without early-life LRTI or with non-RSV LRTI were included. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model to incorporate the possible influences of heterogeneity. Results: Eighteen studies with 266,071 children were included. Compared to children without early-life LRTI, those with RSV-LRTI had a significantly higher risk of asthma (RR =1.88; 95% CI: 1.55 to 2.29; P<0.001; I Conclusions: Early-life RSV-LRTI is associated with an increased risk of asthma compared to children without early-life LRTI. However, RSV does not appear to confer a higher risk of asthma than non-RSV LRTI in early life.
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Registered trials
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