Evidence map›Paper›PMID 41376960›Full record

ArticleJournal of thoracic disease2025

Long-term clinical outcomes of mediastinal lymphoma after surgical resection: reassessing the role of surgery.

Sangil Yun, Chang Hyun Kang, Tae Min Kim, Taeyoung Yun, Ji Hyeon Park, Bubse Na, Kwon Joong Na, Samina Park, Hyun Joo Lee, In Kyu Park and 1 more

Abstract read
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In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sangil YunDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3931-5128
Chang Hyun KangDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1612-1937
Tae Min KimCancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-6145-4426
Taeyoung YunDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4303-8493
Ji Hyeon ParkDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3272-0067
Bubse NaDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3293-1446
Kwon Joong NaDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-4158-9790
Samina ParkDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-9625-2672
Hyun Joo LeeDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3092-2167
In Kyu ParkDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-3550-5554
Young Tae KimDepartment of Thoracic and Cardiovascular Surgery, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-9006-4881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Standard treatment regimens for lymphoma typically involve chemotherapy, often combined with radiation therapy, tailored to the disease's stage and subtype. This study aimed to assess the long-term clinical outcomes of surgical resection of primary mediastinal lymphoma and evaluate the surgery's therapeutic role. Methods: From March 2008 to April 2023, 31 patients at our institution underwent surgery for mediastinal lymphoma, with 26 qualifying for this study after excluding diagnostic-only surgeries. We analyzed early outcomes and overall survival and identified risk factors using Cox regression analysis. Results: Primary operations were performed on 18 patients, while eight underwent salvage operations. There was no operation-related mortality, although two cases had complications. The 5-year overall survival rate was 85.9%, with 100% in the primary and 60% in the salvage operation groups. Subgroup analysis revealed a significantly higher 5-year overall survival rate for complete (R0) resections compared to incomplete resections (94.7% Conclusions: Surgical resection shows promising long-term outcomes for mediastinal lymphoma, particularly for incidentally detected or completely resected tumors. However, the decisions for salvage surgery should be made cautiously, considering the highly selected patient group and employing a multidisciplinary approach.

Indexed as

long-term clinical outcomesmediastinal massPrimary mediastinal lymphomasalvage operationsurgical resection

Identifiers

PMID41376960
PMCPMC12688519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.