Evidence map›Paper›PMID 41376809›Full record

ArticleEuropean urology open science2026

Single-port Robotic Prostatectomy with Neuraxial Anesthesia and Virtual Reality Support: Combining Technologies To Minimize Surgical Impact.

Daniele Amparore, Gabriele Bignante, Enrico Checcucci, Alessandra Saliva, Paolo Alessio, Gabriele Volpi, Michele Sica, Saverio Liguori, Michele Ortenzi, Stefano Zuccolin and 3 more

Abstract readCase Reports
In one paragraph

Article in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Daniele AmparoreDepartment of Oncology, University of Turin, Orbassano, Italy.
Gabriele BignanteDepartment of Oncology, University of Turin, Orbassano, Italy.
Enrico CheccucciDivision of Urology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Alessandra SalivaDivision of Anesthesiology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Paolo AlessioDivision of Urology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Gabriele VolpiDivision of Urology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Michele SicaDivision of Urology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Saverio LiguoriDepartment of Oncology, University of Turin, Orbassano, Italy.
Michele OrtenziDepartment of Oncology, University of Turin, Orbassano, Italy.
Stefano ZuccolinDepartment of Oncology, University of Turin, Orbassano, Italy.
Stefano AlbaDepartment of Urology, Romolo Hospital, Rocca di Neto, Italy.
Alessandro CeruttiDivision of Anesthesiology, Department of Surgery, Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.
Francesco PorpigliaDepartment of Oncology, University of Turin, Orbassano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive surgery continues to evolve to reduce the surgical and anesthetic burden for patients. We present the first prospective pilot case series to assess the feasibility and safety of combining extraperitoneal single-port robot-assisted radical prostatectomy (SP-RARP) with neuraxial anesthesia and intraoperative virtual reality (VR) support. Ten consecutive patients with low-risk prostate cancer underwent SP-RARP under combined spinal-epidural anesthesia and immersive VR distraction offered by the HypnoVR device to enhance patient comfort and reduce anxiety during surgery. Dedicated questionnaires focused on intraoperative HypnoVR tolerability and the patient experience. Data for perioperative parameters and anxiety trends were collected. All procedures were successfully completed without conversion to general anesthesia. Hemodynamic stability was maintained, with only two transient hypotensive episodes managed pharmacologically. Median operative time was 90 min and median hospital stay was 2 d, with no intraoperative or postoperative complications. Pain scores remained negligible (Visual Analog Scale 0/10) and no involuntary movements were reported. Nine patients (90%) completed surgery wearing the HypnoVR visor; most reported better comfort and lower anxiety. State-Trait Anxiety Inventory scores significantly decreased from before surgery to the 24-h postoperative assessment, and Health-Information Technology Usability Evaluation Scale scores confirmed high usability. The study demonstrates that SP-RARP under neuraxial anesthesia combined with VR is safe, feasible, and well accepted, and supports further investigation to validate the impact of this approach on recovery and patient-centered outcomes.

Indexed as

Anxiety reductionEnhanced recoveryExtraperitoneal accessSingle-port surgerySpinal anesthesiaVirtual reality

Identifiers

PMID41376809
PMCPMC12686644

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.