ArticleJournal of oral microbiology2025
Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact and efficacy of systemic antibiotics for peri-implant diseases treatment: A systematic review and meta-analysis on clinical and microbiological outcomes.Periodontology 2000 · 2025Pooled it
- TRABD2A promotes osteogenic differentiation of human periodontal ligament stem cells by modulating TNF-α and IL-1β.Organogenesis · 2026Article
- Diagnostic accuracy of HPV DNA in oral gargle and rinse samples for Head and neck squamous cell carcinoma: A systematic review and meta-analysis.The Japanese dental science review · 2026Review
- Mytilus edulis-mediated green synthesis of selenium nanoparticles with antimicrobial and molluscicidal applications.Scientific reports · 2026Article
- Notch Signalling Pathway in the Pathogenesis of Periodontitis: Research Progress.International dental journal · 2026Review
- Periodontal Disease Burden in China and G20 Nations: Insights From the Global Burden of Disease 2023 Study.International dental journal · 2026Article
- Multimodal Prediction of Periodontitis Using Root Exposure in Intraoral Images and Age.International dental journal · 2026Article
- Revisiting the Oral-Gut Axis: Microbial Symbiosis, Dysbiosis, and Bidirectional Links Between Periodontitis and Inflammatory Bowel Disease.Microorganisms · 2026Review
- Article
- Obesity as a Determinant of Periodontal Therapy Outcomes: Insights on Oxidative and Endoplasmic Reticulum Stress Pathways.International dental journal · 2026Article
- The oral-respiratory interface: modulation ofFuture microbiology · 2026Article
- Increased cardiovascular disease risk in patients with periodontal disease: Insights from studies of periodontal treatment.American heart journal plus : cardiology research and practice · 2026Review
- From dysbiosis to cellular invasion: reassessing the pathogenic role of parvimonas micra in periodontitis as an understudied pathobiont.EBioMedicine · 2026Article
- The Association of Periodontitis with Circadian Rhythm Disorders and Sleep-A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- Hyperuricemia is associated with periodontal ligature dysbiosis in a murine model of experimental periodontitis.Journal of oral microbiology · 2026Article
- Microbial mechanisms and therapeutic interventions in the periodontitis-inflammatory bowel disease axis: a comprehensive review.Journal of oral microbiology · 2026Review
- Association of GSTM1, GSTT1, and GSTP1 Gene Polymorphisms With Susceptibility to Periodontitis: A Systematic Review and Meta-Analysis With Exploratory Analysis of Apical Periodontitis.International journal of dentistry · 2026Review
- Comparison of 16S rRNA gene amplicon and whole-genome shotgun metagenomic sequencing for subgingival oral microbiome profiling.Journal of oral microbiology · 2026Article
- Gingival crevicular fluid as a functionalized point of care for the early detection of dementia or the asymptomatic phase of neurodegeneration.Frontiers in dental medicine · 2025Review
- Incidence of oral disorders and the years lived with disability in Eastern Sub-Saharan Africa, from 1990 to 2023.The journal of medicine accessArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chlorhexidine (CHX) is widely used in oral care for its broad-spectrum antimicrobial activity but can cause significant side effects. Sodium DNA has emerged as a potential adjunct capable of modulating cellular responses. Aim: This study assessed whether sodium DNA enhances the antibacterial and antibiofilm activity of 0.20% and 0.12% CHX mouthwashes against Results: All CHX-containing mouthwashes were bactericidal against Conclusions: This study integrates antimicrobial, antibiofilm, cellular, and metabolomic analyses to assess CHX with sodium DNA. Sodium DNA reduces CHX-induced cytotoxicity and metabolic stress while maintaining antimicrobial activity, offering insights for optimizing oral hygiene formulations through combined microbial and host-cell evaluation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.