Evidence map›Paper›PMID 41376759›Full record

ArticleCureus2025

Acute Bilateral Lower Limb Ischemia Mimicking Neurological Emergency: A Case of Leriche Syndrome.

Bharath Sundaramoorthy, Muthusankar Sudalaimuthu, Suresh Kumar Gopala Pillai

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bharath SundaramoorthyGeneral Medicine, Government Thoothukudi Medical College, Thoothukudi, IND.
Muthusankar SudalaimuthuEmergency Medicine, Swansea Bay University Health Board, Swansea, GBR.
Suresh Kumar Gopala PillaiEmergency Medicine, Morriston Hospital, Swansea, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leriche syndrome, a rare manifestation of chronic aorto-iliac occlusive disease, may occasionally present acutely with bilateral lower limb ischemia, mimicking neurological emergencies such as cauda equina syndrome. We report a 70-year-old man presenting with sudden-onset bilateral lower limb weakness and numbness. Examination revealed cold, pulseless lower limbs. CT angiography demonstrated extensive thrombosis from the descending thoracic aorta to the iliac arteries, with complete occlusion of the right superficial femoral artery. The patient underwent urgent open embolectomy of the femoral and subclavian arteries, aorto-bifemoral bypass via axillary artery anastomoses, and bilateral lower limb fasciotomies. Although perfusion was successfully restored in the left lower limb, irreversible ischemia in the right leg necessitated an above-knee amputation. This case highlights the importance of early recognition of acute aorto-iliac thrombosis, rapid vascular imaging, and coordinated multidisciplinary intervention to optimize outcomes in this rare yet critical vascular emergency.

Indexed as

acute limb ischemiaaortoiliac thrombosisbilateral leg weaknessct angiographyemergency medicineleriche syndromereperfusion timevascular emergency

Identifiers

PMID41376759
PMCPMC12686743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.