Evidence map›Paper›PMID 41376751›Full record

ArticleCureus2025

Investigation of Natural Refractive Changes in Young Hyperopic Children Using Atropine Cycloplegic Refraction.

Toru Kawanobe, Toshiaki Goseki, Shinya Takahashi, Shingo Noda, Yasuhito Ikeda, Eri Ishikawa, Yuichiro Tanaka, Tadahiko Kozawa

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Toru KawanobeOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Toshiaki GosekiOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Shinya TakahashiOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Shingo NodaOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Yasuhito IkedaOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Eri IshikawaOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Yuichiro TanakaOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.
Tadahiko KozawaOphthalmology, Kozawa Eye Hospital and Diabetes Center, Mito, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis retrospective study evaluated refractive error changes following atropine sulfate eye drop use in young children.

methodsPatients under 12 years of age who underwent their first atropine refraction between 2001 and 2021 were included in this study. The objective refractive error changes in children who underwent a second cycloplegic refraction with the same atropine concentration within 18 months of the first refraction were assessed. Refractive errors were compared between patients with myopic (myopic group) and hyperopic (hyperopic group) changes.

resultsAmong the 153 eyes that received two refractive examinations, the refractive error changed by 0.21±0.61 diopters (D). The mean refractive error changes were -0.45±0.34 D and 0.49±0.46 D for the myopic (50 eyes, 33%) and hyperopic (103 eyes, 67%) groups, respectively. The mean refractive errors of the initial refractions were 5.42±2.95 D and 4.18±2.68 D for the myopic and hyperopic groups, respectively (p<0.01).

conclusionThe refractive error changes between the first and second examinations were hyperopic, and in 67% of cases, the refractive error was possibly underestimated during the first examination.

Indexed as

accommodative cycloplegics effectatropinecycloplegic eye dropspediatric patientsrefraction examinationrefractive changeyoung children

Identifiers

PMID41376751
PMCPMC12688528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.