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ArticlePublic health action2025

Can high private cough syrup sales act as a proxy for missed TB notifications in TB surveillance?

K Gupta, H D Shewade, P Manickam, P Soni, V N Baig, R Dagar, M Parmar, Y Saxena, S Charan, H Abdullah and 1 more

Abstract read
In one paragraph

Article in Public health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

K GuptaDepartment of Community Medicine, Geetanjali Medical College and Hospital, Rajasthan, India.ORCID https://orcid.org/https://orcid.org/0000-0003-2382-5323
H D ShewadeDivision of Health Systems Research, ICMRNational Institute of Epidemiology (ICMR-NIE), Chennai, India.
P ManickamDivision of Health Systems Research, ICMRNational Institute of Epidemiology (ICMR-NIE), Chennai, India.
P SoniState TB Cell, Directorate of Medical & Health Services, Jaipur, India.
V N BaigDepartment of Community Medicine, Rajasthan University of Health Sciences College of Medical Sciences, Jaipur, India.
R DagarDepartment of Community Medicine, Ananta Institute of Medical Sciences and Research Centre, Rajsamand, India.
M ParmarDepartment of Community Medicine, GMERS Medical college, Godhra, India.
Y SaxenaDepartment of Community Medicine, Rajasthan University of Health Sciences College of Medical Sciences, Jaipur, India.
S CharanDepartment of Community Medicine, Ananta Institute of Medical Sciences and Research Centre, Rajsamand, India.
H AbdullahKhushi Baby, Jaipur, India.
A K BhardwajDepartment of Community Medicine, M.M. Medical college, Solan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRajasthan in India, is a high TB burden state with a high prevalence to notification ratio. This gap calls for alternative strategies to find the non-notified people with TB. Because cough is the most prominent symptom of TB and cough syrups are one of the highest over the counter drugs in India, its sale might be used as a proxy for missed TB cases.

methodsThis was an ecological study to assess the correlation between cough syrup sales and missed TB notifications in the private sector. We calculated the missed TB notification rate as the difference between the estimated people on TB treatment and TB notification in the private sector from January 2021 to March 2023, across all districts of Rajasthan (n = 33). We analysed district level mean quarterly cough syrup sales and TB notification rates/100,000 population.

resultsWe found positive correlation between cough syrup sales and TB notification [overall (r = 0.43), private (r = 0.63) and missed private TB notification (r = 0.39)]. Based on this analysis, missed TB notification rates were 7x more than the reported notifications in the private sector.

conclusionWe recommend a private sector-based TB surveillance system with TB screening for people who approach pharmacies for cough syrup.

Indexed as

antitussivesIndiaRajasthanSORT ITTB burdentuberculosis

Identifiers

PMID41376680
PMCPMC12687120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.