SynthesisActa dermato-venereologica2025
Longitudinal Melanonychia as a Rare Sign of Invasive Squamous Cell Carcinoma: Case Report and Systematic Review.
Synthesis in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Longitudinal Melanonychia as a Presenting Sign of Onychopapilloma: A Case Report and Review of the Literature.Case reports in dermatological medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 50-year-old male presented with 4-month history of longitudinal melanonychia on the fourth digit of his right foot. A nail matrix and bed biopsy was performed, which led to the diagnosis of invasive well-differentiated squamous cell carcinoma. Immunohistochemical analysis demonstrated positivity for P16 and P40. Longitudinal melanonychia may be a diagnostic challenge, as it can be associated with both benign and malignant conditions. Given the potential for locally aggressive behaviour, squamous cell carcinoma should always be considered in cases of longitudinal melanonychia. A systematic review was conducted in order to analyse all documented cases of invasive squamous cell carcinomas that presented as longitudinal melanonychia, highlighting any associated clinical, dermoscopic, histological, and immunohistochemical characteristics potentially useful for an early identification of this neoplasm.
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Registered trials
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