Evidence map›Paper›PMID 41376045›Full record

ReviewFoods (Basel, Switzerland)2025

Fermented Food-Polysaccharides as Gut Health Regulators: Sources, Optimization, Structural Characteristics and Mechanism.

Aoxiang Zhou, Nanhai Zhang, Huanhuan Dong, Yousheng Huang, Liuming Xie

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Foods (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aoxiang ZhouSchool of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Nanhai ZhangSchool of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Huanhuan DongSchool of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.ORCID 0000-0002-7731-0993
Yousheng HuangSchool of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.
Liuming XieSchool of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China.ORCID 0000-0003-4237-4003

Funding

Early-Career Young Scientists and Technologists Project of Jiangxi Province 20252BEJ730075Jiangxi Provincial Natural Science Foundation 20252BAC200432Jiangxi University of Chinese Medicine Doctoral Research Initiation Grant Subjects 2024BSZR049Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program CXTD-22004
6 · The paper itself

Abstract

Polysaccharides are natural macromolecules with significant functional properties, but the application of certain natural polysaccharides is hindered by their large molecular weight, poor solubility, and limited functionality. In recent years, microbial fermentation has emerged as a sustainable, low-energy-consuming and low-pollution green biotechnology strategy, which degrades and modifies polysaccharides by generating carbohydrate-active enzymes, thereby obtaining new types of polysaccharides with lower molecular weights and stronger functions. Meanwhile, fermented polysaccharides are utilized as prebiotics by intestinal microorganisms. By regulating microbial communities and their metabolites (such as short-chain fatty acids and bile acids), fermented polysaccharides have shown potential value in maintaining metabolic homeostasis and intervening in related diseases. Based on the results of the latest research, this paper summarizes the sources, optimization of fermentation conditions, structural characteristics of fermented food-polysaccharides, with the aim of providing new insights into the utilization of polysaccharides. Meanwhile, focuses on discussing the effects of fermented polysaccharides on the gut microbiota and the mechanisms by which they intervene in disease through regulating the microbiota and its metabolites, which offered new insights and directions for the therapeutic application of fermented food-polysaccharides.

Indexed as

fermentedgut microbiotaintervention mechanismsoptimizationpolysaccharidesstructure

Identifiers

PMID41376045
PMCPMC12691843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.