Comprehensive IAC Cross-Reactivity Validation and Stabilized Method Development for Ochratoxin A, B, and C in Complex Coffee and Spice Matrices.

Jiaojiao Xu, Zengxuan Cai, Mengli Wang, Xiaomin Xu, Haitao Shen

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaojiao XuZhejiang Provincial Center of Disease Control and Prevention, Hangzhou 310051, China.ORCID 0000-0001-6697-5968

Zengxuan CaiZhejiang Provincial Center of Disease Control and Prevention, Hangzhou 310051, China.ORCID 0000-0003-1454-8758

Mengli WangZhejiang Provincial Center of Disease Control and Prevention, Hangzhou 310051, China.

Xiaomin XuZhejiang Provincial Center of Disease Control and Prevention, Hangzhou 310051, China.

Haitao ShenZhejiang Provincial Center of Disease Control and Prevention, Hangzhou 310051, China.

Funding

Zhejiang Provincial Natural Science Foundation LTGC23H260001

6 · The paper itself

Abstract

Ochratoxins (OTs) pose a major food safety threat, yet analytical methodologies and regulations focus almost exclusively on ochratoxin A (OTA), overlooking the toxic analogues OTB and OTC, especially in complex coffee and spice matrices. The present study addressed this gap by first systematically confirming the high cross-reactivity (>85%) of commercial OTA immunoaffinity columns (IACs) toward OTB and OTC. It was identified that conventional alkaline methanol extraction caused OTC degradation, and subsequently a stable and unified acetonitrile-water (8/2,

Indexed as

coffeeIAC cross-reactivityochratoxin Aochratoxin Bochratoxin Cochratoxinsspices

Identifiers

PMID41376038

DOI10.3390/foods14234102

PMCPMC12692647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.