Evidence map›Paper›PMID 41376027›Full record

ArticleFoods (Basel, Switzerland)2025

Host Dietary Nutrients Shape GH32-Mediated Microbial Responses to Prebiotic Fructans: A Randomized Trial.

Hideaki Takahashi, Tadashi Fujii, Chikako Yamada, Nobuhiro Kondo, Kento Kuramitsu, Kohei Funasaka, Eizaburo Ohno, Yoshiki Hirooka, Takumi Tochio, Kotoyo Fujiki

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Antioxidant and Anti-Inflammatory Activities of Probiotic Strains.International journal of molecular sciences · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hideaki TakahashiGraduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Nisshin 470-0196, Japan.
Tadashi FujiiDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.
Chikako YamadaGraduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Nisshin 470-0196, Japan.
Nobuhiro KondoDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.
Kento KuramitsuDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.ORCID 0009-0005-2475-1380
Kohei FunasakaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.
Eizaburo OhnoDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.
Yoshiki HirookaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.ORCID 0000-0001-9639-7425
Takumi TochioDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Japan.
Kotoyo FujikiGraduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Nisshin 470-0196, Japan.

Funding

JSPS KAKENHI JP24K14784The Anzu no Mori Foundation 2024 Research Grant No grant number
6 · The paper itself

Abstract

Prebiotics, such as short- and long-chain fructans, beneficially modulate the microbiota; however, individual variability in response remains unclear. In this randomized, double-blind, placebo-controlled trial, 40 healthy adults received either a combined fructan supplement-1-Kestose (Kes) and inulin (Inu)-or a placebo (maltose + cornstarch) for 4 weeks. We investigated the fecal microbiome, bacterial growth, and glycoside hydrolase family 32 (GH32) gene abundance, and further examined the association between dietary intake and GH32. Kes and Inu co-supplementation selectively increased

Indexed as

Bifidobacterium adolescentisBifidobacterium longumglycoside hydrolase family 32 (GH32)gut microbiotaprebiotics

Identifiers

PMID41376027
PMCPMC12692294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.