Evidence map›Paper›PMID 41375950›Full record

ArticleFoods (Basel, Switzerland)2025

Anti-Skin Aging Potential of Methoxyflavones from

Si-Young Ahn, Se Yun Jeong, Bum Soo Lee, Yun Seok Joh, Hamed Hamishehkar, Sullim Lee, Ki Hyun Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Si-Young AhnDepartment of Life Science, College of Bio-Nano Technology, Gachon University, Seongnam 13120, Republic of Korea.
Se Yun JeongSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Bum Soo LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Yun Seok JohSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Hamed HamishehkarDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz 51368, Iran.
Sullim LeeDepartment of Life Science, College of Bio-Nano Technology, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0000-0002-4187-2177
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-5285-9138

Funding

National Research Foundation of Korea RS-2019-NR040057 and RS-2021-NR059240
6 · The paper itself

Abstract

Reactive oxygen species (ROS) generated by ultraviolet (UV) radiation accelerate skin aging by activating matrix metalloproteinase-1 (MMP-1) and mitogen-activated protein kinase (MAPK) signaling pathways. Therefore, antioxidants that can suppress ROS generation and downstream signaling cascades are considered promising anti-aging agents. In this study, five methoxyflavones were isolated from

Indexed as

anti-skin agingKaempferia parvifloramethoxyflavonesnormal human dermal fibroblastsTNF-α

Identifiers

PMID41375950
PMCPMC12691992

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.