Evidence map›Paper›PMID 41375947›Full record

ArticleFoods (Basel, Switzerland)2025

Anti-Metabolic Dysfunction-Associated Hepatic Steatosis Effects of Pickering Emulsion-Encapsulated Curcumin via Gut Microbiota and Short-Chain Fatty Acids Modulation in High-Fat-Diet Mice.

Lisha Niu, Fengyang Wu, Yingxue Jiao, Chi Ren, Ying Shu, Yi Liu, Kaixuan Zhao, Weili Rao, Liwen Wang, Zhisheng Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lisha NiuCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Fengyang WuCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Yingxue JiaoCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Chi RenCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Ying ShuCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Yi LiuBaoding Product Quality Supervision and Inspection Institute, Baoding 071000, China.
Kaixuan ZhaoCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Weili RaoCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Liwen WangCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.
Zhisheng ZhangCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.ORCID 0000-0001-6349-5627
Wenhui QiCollege of Food Science and Technology, Hebei Agricultural University, Lekai South Avenue, Baoding 071000, China.ORCID 0000-0002-0180-265X

Funding

the Basic Research Funds of Hebei Provincial Colleges and Universities KY2022013the earmarked fund for Hebei Agriculture Research System HBCT2024250205the Natural Science Foundation of Hebei Province C2023204010the Research Foundation for the Introduced Talents of Hebei Agricultural University YJ2021025
6 · The paper itself

Abstract

With lipid metabolism disorders becoming a global health issue, designing safe and effective prevention methods is crucial. Curcumin, a natural polyphenol compound, exhibits the ability to ameliorate lipid metabolism disorders. However, the bioavailability of curcumin is low, primarily due to its poor solubility, susceptibility to degradation, low absorption, and rapid metabolism. The bioavailability of curcumin is markedly enhanced when it is encapsulated within Pickering emulsions. This study investigated the ameliorative effect of curcumin encapsulated in Pickering emulsions on high-fat-diet-induced lipid metabolism disorders. We demonstrated that curcumin encapsulated in Pickering emulsions substantially prevented high-fat-diet-induced body gain, alleviated glucose intolerance, mitigated insulin resistance, and improved hepatic steatosis. Curcumin encapsulated in Pickering emulsions induced gut microbiota remodeling, characterized by an increased relative abundance of Bacteroidetes and a decreased relative abundance of Firmicutes. In particular, the relative abundance of

Indexed as

gut microbiotametabolic dysfunction-associated hepatic steatosispickering emulsion-encapsulated curcuminshort-chain fatty acids

Identifiers

PMID41375947
PMCPMC12692576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.