Evidence map›Paper›PMID 41375918›Full record

ReviewJournal of clinical medicine2025

Spinal Cord Stimulation: Mechanisms of Action, Indications, Types, Complications.

Chrysoula Vlachou, Despoina Sarridou, Vasilios Grosomanidis, Ilias Voulgaris, Helena Argiriadou, Aikaterini Amaniti

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chrysoula VlachouFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.ORCID 0009-0003-3062-8739
Despoina SarridouFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.ORCID 0000-0003-4810-3829
Vasilios GrosomanidisFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.
Ilias VoulgarisFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.
Helena ArgiriadouFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.
Aikaterini AmanitiFaculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Stilponos Kyriakidi St., 546 36 Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in neuromodulation are opening new pathways for treating chronic pain, with spinal cord stimulation (SCS) poised for substantial transformation in the coming years. Evolving technologies and a deeper understanding of pain mechanisms are driving a move away from traditional, standardized stimulation models toward more precise and personalized interventions. This shift reflects not only technical progress but also a growing emphasis on tailoring treatment to individual patient profiles. Advances in neuromodulation have introduced new stimulation patterns such as high-frequency, burst and dorsal root ganglion stimulation, which developed to address the limitations of conventional tonic SCS, especially declining long-term efficacy and the need for paresthesia. Early studies show promising results for these newer modalities, but findings are inconsistent and long-term data remain limited. In this article, we explore the current landscape of SCS innovation, highlight emerging clinical approaches and discuss the conceptual and technological trends that are likely to redefine the role of neuromodulation in chronic pain management.

Indexed as

chronic painneuromodulationspinal cord stimulationspinal neurosurgery

Identifiers

PMID41375918
PMCPMC12692890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.