Evidence map›Paper›PMID 41375874›Full record

ReviewJournal of clinical medicine2025

Cucurbiturils in Oxygen Delivery and Their Potential in Anemia Management.

Daniel Papiu, Alexandra Nadaban, Adelina Palcu, Alciona Sasu, Gabriela Mara, Paul Albu, Casiana Boru, Coralia Cotoraci

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel PapiuMultidisciplinary Doctoral School, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Alexandra NadabanDepartment of Hematology, Faculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Adelina PalcuDepartment of Hematology, Faculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Alciona SasuDepartment of Hematology, Faculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Gabriela MaraPneumology Department, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Paul AlbuDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Vasile Goldis Western University of Arad, 86 L. Rebreanu St., 310414 Arad, Romania.
Casiana BoruDepartment of Obstetrics and Gynecology, Faculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.ORCID 0009-0004-1725-3749
Coralia CotoraciDepartment of Hematology, Faculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient oxygen transport and accurate anemia diagnostics remain significant medical challenges, as current therapies suffer from stability limitations, immunogenic risks, and inadequate sensitivity. Cucurbiturils (CB[n]), a family of pumpkin-shaped supramolecular macrocycles, present promising solutions due to their rigid architecture, hydrophobic cavities, and strong host-guest binding properties. Functional derivatives such as perhydroxy-cucurbit[5]uril can reversibly bind dioxygen under physiological conditions, highlighting their potential as synthetic hemoglobin substitutes. Additionally, cucurbituril-based probes for Fe

Indexed as

anemia diagnostics and therapybiocompatibilitycucurbiturilsoxygen carrierssupramolecular chemistry

Identifiers

PMID41375874
PMCPMC12693383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.