Evidence map›Paper›PMID 41375825›Full record

ArticleJournal of clinical medicine2025

Protocol for a Single-Arm Pilot Clinical Trial: Developing and Evaluating a Machine Learning Opioid Prediction & Risk-Stratification E-Platform (DEMONSTRATE).

Je-Won J Hong, Debbie L Wilson, Khoa Nguyen, Walid F Gellad, Julie Diiulio, Laura Militello, Shunhua Yan, Christopher A Harle, Danielle Nelson, Eric I Rosenberg and 7 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06810076 (Developing and Evaluating a Machine-Learning Opioid Prediction & Risk-Stratification E-Platform), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06810076 naactive not recruitingnot on this map

Developing and Evaluating a Machine-Learning Opioid Prediction & Risk-Stratification E-Platform (DEMONSTRATE)

TypeinterventionalSponsorUniversity of PittsburghRan2025 to 2026Enrolled674ConditionsOpiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related DisordersArmsMachine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Je-Won J HongDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Debbie L WilsonDepartment of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.
Khoa NguyenDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Walid F GelladDivision of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Julie DiiulioApplied Decision Science, Cincinnati, OH 45212, USA.ORCID 0000-0002-5791-0705
Laura MilitelloApplied Decision Science, Cincinnati, OH 45212, USA.ORCID 0000-0001-8445-5640
Shunhua YanDivision of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Christopher A HarleDepartment of Health Policy and Management, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN 46202, USA.
Danielle NelsonDepartment of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0003-1261-239X
Eric I RosenbergDivision of General Internal Medicine, Department of Medicine, College of Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0002-5396-0422
Siegfried SchmidtDepartment of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0001-5941-6009
Chung-Chou Ho ChangDivision of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0003-3665-6928
Gerald CochranDivision of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA.
Yonghui WuHealth Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL 32611, USA.
Stephanie A S StarasHealth Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL 32611, USA.
Courtney KuzaCenter for Pharmaceutical Policy and Prescribing, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Wei-Hsuan Lo-CiganicDivision of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0001-6590-4770

Funding

JCM APCNIDA NIH HHS R01DA05067NIH National Center for Advancing Translation Sciences REDCap UL1TR001427
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clinical decision supportmachine learningopioid overdoseprimary care

Identifiers

PMID41375825
PMCPMC12693449

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.