Evidence map›Paper›PMID 41375583›Full record

ArticleJournal of clinical medicine2025

Endoscopic Endonasal Repair of Bilateral Choanal Atresia in a Neonate with Placement of a Steroid-Eluting Bioabsorbable Nasal Stent (PROPEL) Using a Customised Alternative Insertion Technique: A Case Report and Literature Review.

Cosimo Galletti, Daniele Portelli, Maria Grazia Ferrisi, Fabiana Gambino, Laura Iuculano, Benedetto Sanfilippo, Gianluca Ielo, Leonard Freni, Antonino Maniaci, Francesco Ciodaro and 3 more

Abstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cosimo GallettiDepartment of Medicine and Surgery, University of Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.ORCID 0000-0002-7226-4596
Daniele PortelliUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.ORCID 0000-0003-2134-8535
Maria Grazia FerrisiUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Fabiana GambinoUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Laura IuculanoUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Benedetto SanfilippoUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Gianluca IeloUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Leonard FreniUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Antonino ManiaciDepartment of Medicine and Surgery, University of Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.ORCID 0000-0002-1251-0185
Francesco CiodaroUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.
Francesco FreniUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.ORCID 0000-0001-5664-7493
Francesco GallettiDepartment of Otorhinolaryngology, University of Messina, Piazza Pugliatti 1, 98122 Messina, Italy.
Bruno GallettiUnit of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina Via Consolare Valeria 1, 98125 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBilateral congenital choanal atresia (CCA) is a rare, life-threatening condition in neonates. This is the first reported case of PROPEL steroid-eluting stent use in a seven-day-old bilateral CCA neonate, with a customised technique developed to overcome limitations of the standard applicator. CASE PRESENTATION: A full-term male neonate presented with severe respiratory distress and was diagnosed with bilateral CCA. Endoscopic repair with mucoperiosteal flaps and drilling of the atretic plate was performed, followed by placement of a tailored PROPEL stent using a modified insertion with a Nelaton tube system. OUTCOMES: Recovery was uneventful. At 30 days, the stent remained well-positioned; at two, three, and six months, the neochoana was patent with no restenosis or synechiae.

conclusionsThe PROPEL stent, combined with a customised insertion method, may offer a promising alternative for neonatal CCA repair. Further studies are needed to assess long-term outcomes and safety.

Indexed as

bilateral choanal atresiacase reportendoscopic nasal surgerynasal stentpropel

Identifiers

PMID41375583
PMCPMC12693482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.