Evidence map›Paper›PMID 41375523›Full record

ArticleAnimals : an open access journal from MDPI2025

Using Whole-Genome Sequencing Data Reveals the Population Structure and Selection Signatures for Reproduction Traits in Duolang Sheep.

Keyao Wang, Qianjun Li, Zhigang Niu, Zhengfen Xue, Shiyuan Li, Jiabao Yan, Yang Chen, Yanlong Zhang, Hongcai Shi, Xiangdong Ding

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keyao WangState Key Laboratory of Animal Biotech Breeding/National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Qianjun LiState Key Laboratory of Animal Biotech Breeding/National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Zhigang NiuKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.ORCID 0000-0003-3570-8490
Zhengfen XueKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.
Shiyuan LiState Key Laboratory of Animal Biotech Breeding/National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Jiabao YanKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.
Yang ChenKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.
Yanlong ZhangKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.
Hongcai ShiKey Lab of Reproduction & Breeding Biotechnology of Grass Feeding Livestock of MOA, Xinjiang Academy of Animal Science, Urumqi 830000, China.
Xiangdong DingState Key Laboratory of Animal Biotech Breeding/National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.

Funding

the Major science and technology projects in Xinjiang Uygur autonomous region No. 2023A02004the Major science and technology projects in Xinjiang Uygur autonomous region No. 2024A02004the Tianshan Talent Training Program-high-level talents for the advancement of modern agriculture and animal husbandry No. 2024SNGGGCC06
6 · The paper itself

Abstract

Duolang sheep, a meat-fat dual-purpose breed indigenous to Xinjiang, China, has been cultivated traditionally by the local Uyghur people for its prolificacy and precocious sexual maturity, while little research on the population structure and trait inheritance characteristics of Duolang sheep is available. This study employed whole-genome resequencing data from a cohort of 60 Duolang sheep to dissect their genetic population structure and genes related to reproductive traits. A total of 1565 Gb of high-quality data with an average depth of 14.06× was generated. After SNP calling and quality control, 31,300,060 SNPs were identified. Following linkage disequilibrium (LD)-based pruning, a total of 4,479,177 high-quality SNPs were retained for subsequent analyses. Based on these SNPs, the internal genetic structure of the Duolang sheep population was elucidated, with 14 kinship outliers detected through principal component analysis (PCA). Furthermore, LD decay analysis revealed that the r

Indexed as

duolang sheeppopulation genetic structurereproductive traitsselection signatures

Identifiers

PMID41375523
PMCPMC12691290

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.