Evidence map›Paper›PMID 41375439›Full record

ArticleAnimals : an open access journal from MDPI2025

Effects of Adding Butyrate or Exogenous Fibrolytic Enzymes on Ruminal Epithelium, Metabolism, and Microbiota of Beef Cattle.

Daniel Moretto Casali, Kalista Eloisa Loregian, Leandro Aparecido Ferreira da Silva, Ana Laura Januário Lelis, Rodrigo José de Oliveira, Daniel Hideki Mariano Watanabe, Johnny Maciel Souza, Garret Suen, Danilo Domingues Millen

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel Moretto CasaliSchool of Agricultural Sciences, São Paulo State University (UNESP), Botucatu 18618-618, SP, Brazil.ORCID 0000-0001-9795-6874
Kalista Eloisa LoregianSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0000-0003-2327-121X
Leandro Aparecido Ferreira da SilvaSchool of Agricultural Sciences, São Paulo State University (UNESP), Botucatu 18618-618, SP, Brazil.ORCID 0000-0001-6604-803X
Ana Laura Januário LelisSchool of Agricultural Sciences, São Paulo State University (UNESP), Botucatu 18618-618, SP, Brazil.ORCID 0000-0003-4592-7566
Rodrigo José de OliveiraSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0009-0002-4049-1038
Daniel Hideki Mariano WatanabeSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0009-0001-2166-6149
Johnny Maciel SouzaSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0000-0003-1693-5014
Garret SuenDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI 53707, USA.ORCID 0000-0002-6170-711X
Danilo Domingues MillenSchool of Agricultural and Veterinary Sciences, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.ORCID 0000-0002-1253-7310

Funding

Adisseo (São Paulo, Brazil) 0Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/14826-4
6 · The paper itself

Abstract

Feedlot cattle produce high concentrations of short-chain fatty acids (SCFAs) through ruminal fermentation, with butyrate playing a crucial role in epithelial development and SCFA absorption. This study evaluated the effects of dietary sodium butyrate or exogenous fibrolytic enzymes on the ruminal epithelium and microbiota. Three rumen-cannulated Aberdeen Angus steers were assigned to a replicated 3 × 3 Latin square design, totaling six experimental periods. Each period lasted 28 d, comprising 14 d of adaptation and 14 d of finishing. Diets only differed in additive inclusion: CON-control; ENZ-exogenous enzyme complex (0.01% of the dry matter [DM]); BUT-sodium butyrate (0.3% DM during adaptation; 0.1% during finishing). The ENZ reduced the ruminal temperature (

Indexed as

additivesfeed additivesmetabolismmicrobiologyruminal papillae

Identifiers

PMID41375439
PMCPMC12691087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.