Evidence map›Paper›PMID 41375200›Full record

ArticleMolecules (Basel, Switzerland)2025

Green Contributions to the Chemistry of Perezone and Oxidation of the Double Bond of the Side Chain: A Theoretical Study and Cytotoxic Evaluation in MDA-MB231 Cells.

René Gerardo Escobedo-González, Joel Martínez, Adriana L Rivera-Espejel, Claudia L Vargas-Requena, María Inés Nicolás-Vázquez, René Miranda Ruvalcaba

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

René Gerardo Escobedo-GonzálezDepartment of Industrial Maintenance and Nanotechnology, Technological University of Juarez City, City of Juarez 32695, Chihuahua State, Mexico.ORCID 0000-0002-0640-0705
Joel MartínezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, State of Mexico, Mexico.ORCID 0000-0002-6683-6738
Adriana L Rivera-EspejelDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, State of Mexico, Mexico.
Claudia L Vargas-RequenaInstitute of Biomedical Science, Autonomous University of the City of Juarez (UACJ), City of Juarez 32315, Chihuahua State, Mexico.ORCID 0000-0001-7612-1616
María Inés Nicolás-VázquezDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, State of Mexico, Mexico.ORCID 0000-0003-0722-5045
René Miranda RuvalcabaDepartamento de Ciencias Químicas, Facultad de Estudios Superiores Cuautitlán Campo 1, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, State of Mexico, Mexico.

Funding

National Autonomous University of Mexico, grant number PAPIIT IN 221514-3/14-17
6 · The paper itself

Abstract

Perezone, a sesquiterpene quinone, was the first natural product isolated in crystalline form on the American continent in 1852. It is commonly found in the roots of herbs from the Acourtia species (formerly

Indexed as

Green Chemistry TechnologySesquiterpenesCell Line, TumorHumansMolecular Docking SimulationMolecular StructureOxidation-ReductionSesquiterpenesantineoplastic compoundschemoinformatic studyDFT studygreen approachmolecular dockingperezone-isoperezone

Identifiers

PMID41375200
PMCPMC12693026

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.