Discrimination of Rheumatoid and Psoriatic Arthritis Based on Raman and NIR Spectra Using Machine-Learning Algorithms.

Przemysław Cuprych, Izabela Kokot, Roman Szostak, Ewa Maria Kratz, Sylwester Mazurek

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Przemysław CuprychDepartment of Chemistry, University of Wroclaw, F. Joliot-Curie, 50-383 Wroclaw, Poland.ORCID 0009-0002-7346-604X

Izabela KokotDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211A, 50-556 Wroclaw, Poland.ORCID 0000-0002-3711-8614

Roman SzostakDepartment of Chemistry, University of Wroclaw, F. Joliot-Curie, 50-383 Wroclaw, Poland.

Ewa Maria KratzDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211A, 50-556 Wroclaw, Poland.ORCID 0000-0003-2948-4574

Sylwester MazurekDepartment of Chemistry, University of Wroclaw, F. Joliot-Curie, 50-383 Wroclaw, Poland.ORCID 0000-0002-8096-5229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are chronic autoimmune diseases. They share similar symptoms. The lack of specific markers can lead to misdiagnosis. Using spectroscopic information on the chemical composition of body fluids can effectively differentiate these diseases. The discriminant analysis results are presented based on Raman and near-infrared (NIR) spectra of freeze-dried blood sera. The performance of partial least squares discriminant analysis (PLS-DA) and counter-propagation artificial neural network (CP-ANN) techniques in differentiation between RA (

Indexed as

Arthritis, PsoriaticArthritis, RheumatoidMachine LearningSpectrum Analysis, RamanAdultAlgorithmsDiscriminant AnalysisFemaleHumansLeast-Squares AnalysisMaleMiddle AgedNeural Networks, ComputerSpectroscopy, Near-Infrareddiscriminant analysismachine learningNIR spectroscopypsoriatic arthritisRaman spectroscopyrheumatoid arthritis

Identifiers

PMID41375111

DOI10.3390/molecules30234513

PMCPMC12693699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.