Evidence map›Paper›PMID 41375069›Full record

ArticleCancers2025

Does Joint Care Impact Teenage and Young Adult's Patient-Reported Outcomes After a Cancer Diagnosis? Results from BRIGHTLIGHT_2021.

Lorna A Fern, Elysse Bautista-Gonzalez, Julie A Barber, Jamie Cargill, Richard G Feltbower, Laura Haddad, Maria Lawal, Martin G McCabe, Safia Samih, Louise Soanes and 3 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lorna A FernCancer Clinical Trials Unit, University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.ORCID 0000-0003-4821-8466
Elysse Bautista-GonzalezCentre for Nurse, Midwife and AHP Led Research (CNMAR), University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.ORCID 0000-0002-8925-4706
Julie A BarberDepartment of Statistical Science, University College London, London WC1E 6BT, UK.
Jamie CargillManaged Service Network for Children and Young People with Cancer in Scotland, Kings Cross Hospital, Dundee DD3 8EA, UK.ORCID 0009-0001-8575-6856
Richard G FeltbowerLeeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0002-1728-9408
Laura HaddadPatient Representative, BRIGHTLIGHT Young Advisory Panel.
Maria LawalPatient Representative, BRIGHTLIGHT Young Advisory Panel.
Martin G McCabeDivision of Cancer Sciences, The University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-5138-0707
Safia SamihCancer Clinical Trials Unit, University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.
Louise SoanesTeenage Cancer Trust, London WC1V 7AA, UK.
Dan P StarkLeeds Institute of Medical Research at St James's, Leeds LS9 7TF, UK.
Cecilia Vindrola-PadrosRapid Research Evaluation and Appraisal Lab (RREAL), Department of Targeted Intervention, University College London, London WC1E 6BT, UK.
Rachel M TaylorCentre for Nurse, Midwife and AHP Led Research (CNMAR), University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.ORCID 0000-0002-0853-0925

Funding

National Institute for Health and Care Research NIHR201438National Institute for Health and Care Research NIHR304515
6 · The paper itself

Abstract

backgroundHealthcare policy in the United Kingdom recognizes that teenagers and young adults (TYA:16-24 years at diagnosis) require specialist care. In England, Principal Treatment Centers (PTCs) exist, delivering enhanced care exclusively within the PTC or as 'joint care' with designated hospitals (DHs). We examined whether joint care impacted patient-reported outcomes when compared to care at one site.

methodsA cross-sectional survey was conducted in England, Scotland, and Wales. This included validated measures of quality of life (QoL), anxiety and depression, health status, social support, and illness perception. Comparisons were made based on young people's exposure to specialist care within 6 months of diagnosis, defined as care in a TYA PTC: all-TYA-care (all care in a TYA unit), no-TYA-care (no care in a TYA unit, care delivered in a children's/adult unit only), and joint-care (care in a TYA-PTC and in a children's/adult unit).

resultsOverall, 260/1009 (25.8%) participants responded (England n = 241; Scotland/Wales n = 19). Due to different healthcare policies, statistical analysis was applied to England only. Mean QoL scores were <69.7, the threshold indicating impaired QoL (mean 58.65, standard deviation 20.13). After adjustment for confounding factors, no clinically significant differences in mean QoL between categories existed. The adjusted mean difference for all-TYA-care (n = 66) versus no-TYA-care (n = 89) was -2.28 units (95% confidence interval (CI: -8.85 to 4.29) and for joint-care versus no-TYA-care (n = 85), -4.35 units (CI: -10.34 to 1.63). Similarly, no notable differences in social support, anxiety, depression, or illness perception between categories existed. Patients receiving all-TYA-care had a lower average health status compared with no-TYA-care (difference in means -0.09 (CI:-0.18 to -0.01).

conclusionsNo evidence that patient-reported outcomes differ by categories of care existed. This may suggest the evolution of TYA cancer services has led to similar outcomes regardless of care category. However, given the small sample size it is not possible to draw firm conclusions.

Indexed as

BRIGHTLIGHTcancerpatient-reported outcomesquality of lifeteenagersyoung adultsyoung people

Identifiers

PMID41375069
PMCPMC12691178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.