Evidence map›Paper›PMID 41375004›Full record

ArticleCancers2025

Dynamic PD-L1 Regulation Shapes Tumor Immune Escape and Response to Immunotherapy.

Bruce Pell, Aigerim Kalizhanova, Aisha Tursynkozha, Denise Dengi, Ardak Kashkynbayev, Yang Kuang

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Do Metastatic Cells Arise from PD-L1International journal of molecular sciences · 2026
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Bruce PellDepartment of Mathematics and Computer Science, Lawrence Technological University, Southfield, MI 48075, USA.ORCID 0000-0003-1358-8061
Aigerim KalizhanovaDepartment of Mathematics, Nazarbayev University, 010000 Astana, Kazakhstan.
Aisha TursynkozhaDepartment of Artificial Intelligence and Data Science, Astana IT University, 010000 Astana, Kazakhstan.
Denise DengiDepartment of Mathematics, University of California Berkeley, Berkeley, CA 94720, USA.
Ardak KashkynbayevDepartment of Mathematics, Nazarbayev University, 010000 Astana, Kazakhstan.ORCID 0000-0002-1338-2058
Yang KuangSchool of Mathematical and Statistical Sciences, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0003-2774-4133

Funding

A wastewater approach to viral transmission, evolution, and ecologyR01AI192873 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Fuqing Wu · 2025 to 2026
$1.1M
NIAID NIH HHS R01 AI192873
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adaptive immune responsecancer immunotherapydifferential equationsimmunostimulantmath modelmodelingPD-L1

Identifiers

PMID41375004
PMCPMC12691448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.