Evidence map›Paper›PMID 41374977›Full record

ArticleCancers2025

Comprehensive Detection of Chromosomal and Genomic Abnormalities via Next-Generation Sequencing-Based Genomic Proximity Mapping Improves Diagnostic Classification of Hematologic Neoplasms.

Xueyan Chen, He Fang, Yu Wu, Soheil Meshinchi, Kikkeri N Naresh, Emily Reister, Kyle Langford, Stephen M Eacker, Yajuan J Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xueyan ChenDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-5119-6822
He FangDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-9036-8092
Yu WuDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.ORCID 0009-0005-1034-9737
Soheil MeshinchiTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Kikkeri N NareshDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-3807-3638
Emily ReisterPhase Genomics, Seattle, WA 98109, USA.
Kyle LangfordPhase Genomics, Seattle, WA 98109, USA.ORCID 0009-0008-9226-7218
Stephen M EackerPhase Genomics, Seattle, WA 98109, USA.ORCID 0000-0002-9678-1192
Yajuan J LiuDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.

Funding

AI-based AML risk stratification using next generation cytogenomicsR44CA278140 · NCI · PHASE GENOMICS, INC. · PI EACKER, STEPHEN MATTHEW · 2023 to 2024
$2.0M
Chromosomal aberration detection in FFPE tissue using proximity ligation sequencingR44CA281528 · NCI · PHASE GENOMICS, INC. · PI EACKER, STEPHEN MATTHEW · 2023 to 2024
$2.0M
NCI NIH HHS R44 CA278140NCI NIH HHS R44 CA281528NCI NIH HHS R44CA281528 and R44CA278140
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

copy number alterationsgene fusionsgenomic proximity mappingHi-C sequencinglymphomamyeloid neoplasmstructural variants

Identifiers

PMID41374977
PMCPMC12691235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.