Evidence map›Paper›PMID 41374975›Full record

ArticleCancers2025

Histotripsy Dose Impacts Treated Tumor Immune Infiltration and Survival Outcomes in a Murine B16F10 Melanoma Model.

Reliza McGinnis, Brian Song, Hanna Kim, Anna Lorenzon, Jiaqi Shi, Lili Zhao, Clifford S Cho, Anutosh Ganguly, Zhen Xu

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Histotripsy for Liver Tumors: Breakthrough or Hype?Annals of surgical oncology · 2026
    Article
  2. Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Reliza McGinnisDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-2508-5050
Brian SongDepartment of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Hanna KimDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-0654-2949
Anna LorenzonDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Jiaqi ShiDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-4893-1587
Lili ZhaoDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-6366-8206
Clifford S ChoDepartment of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-9577-7626
Anutosh GangulyDepartment of Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Zhen XuDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-0262-3044

Funding

Ultrasound-guided Ultra-steerable Histotripsy Array System for Non-invasive treatment of Soft Tissue SarcomaR01EB034399 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Zhen Xu · 2023 to 2026
$2.2M
Acoustic Cavitation Emission (ACE) Feedback Methods for Monitoring Histotripsy-Induced Tissue Fractionation In SituR01EB032772 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUKOVICH, JONATHAN ROBERT · 2022 to 2025
$2.0M
Harnessing the therapeutic potential of histotripsy focused ultrasound-induced immunogenic cancer cell deathR01CA269394 · NCI · VAN ANDEL RESEARCH INSTITUTE · PI Clifford Cho · 2023 to 2026
$1.8M
NIH HHS R01 CA269394NIH HHS R01 EB032772NIH HHS R01 EB034399
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B16F10 melanomacancer immunologydose studyFUShistotripsy

Identifiers

PMID41374975
PMCPMC12691148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.