Evidence map›Paper›PMID 41374737›Full record

ArticleSensors (Basel, Switzerland)2025

Molecularly Imprinted Membranes: Dual@MIPs@mbr for On-Site Detection of CA 19-9.

Eduarda Rodrigues, Ana Xu, Paula Sampaio, Rafael C Castro, David S M Ribeiro, João L M Santos, Ana Margarida L Piloto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eduarda RodriguesCIETI-LabRISE, ISEP, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal.
Ana XuCIETI-LabRISE, ISEP, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal.
Paula Sampaioi3S-Institute of Research and Innovation in Health, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-1148-2159
Rafael C CastroLAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira No 228, 4050-313 Porto, Portugal.ORCID 0000-0002-8722-3172
David S M RibeiroLAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira No 228, 4050-313 Porto, Portugal.ORCID 0000-0001-7879-0143
João L M SantosLAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira No 228, 4050-313 Porto, Portugal.
Ana Margarida L PilotoCIETI-LabRISE, ISEP, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal.ORCID 0000-0002-2374-2467

Funding

Fundação para a Ciência e Tecnologia https://doi.org/10.54499/2022.07897.PTDCFundação para a Ciência e Tecnologia SFRH/BPD/116067/2016Fundação para a Ciência e Tecnologia Tenure Program - 1st Edition (Call Reference PRR No. 02/C06-i06/2024)PPBI-Portuguese Platform of Bioimaging PPBI-POCI-01-0145-FEDER-022122
6 · The paper itself

Abstract

Dual-emission molecularly imprinted membranes (dual@MIPs@mbr) were developed as a proof-of-concept platform for the selective and instrument-free detection of the cancer biomarker carbohydrate antigen 19-9 (CA 19-9). The system integrates a ratiometric fluorescence response by embedding yellow-emitting quantum dots (y-QDs), serving as target-responsive probes, and blue-emitting carbon dots (b-CDs), acting as an internal reference, within a CA 19-9-imprinted polymeric matrix. Specific rebinding of CA 19-9 to the imprinted cavities induced selective quenching of the y-QDs while preserving the b-CDs emission, yielding a visible color shift from yellow/green to blue. This behavior enabled the quantification of CA 19-9 over a linear range of 4-400 U mL

Indexed as

Biosensing TechniquesCA-19-9 AntigenMolecular ImprintingMolecularly Imprinted PolymersCarbonHumansLimit of DetectionMembranes, ArtificialPolymersQuantum DotsCA-19-9 AntigenCarbonMembranes, ArtificialMolecularly Imprinted PolymersPolymerscarbohydrate antigen CA 19-9dual-emission molecularly imprinted membranes (dual@MIPs@mbr)point-of-care detectionquantum dots (QDs)

Identifiers

PMID41374737
PMCPMC12694677

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.