ArticleDiagnostics (Basel, Switzerland)2025
Granzyme B PET Imaging Enables Detection of CAR T-Cell Therapy Response in a Human Melanoma Mouse Model.
Priska Summer, Niklas Bulmer, Suma Prabhu, Naomi Gallon, Rebecca C Larson, Marcela V Maus, Umar Mahmood, Pedram Heidari
Abstract read
In one paragraphArticle in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Priska SummerDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-3779-2895 Niklas BulmerDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
Suma PrabhuDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-6856-7271 Naomi GallonDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.
Rebecca C LarsonCellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Marcela V MausCellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Umar MahmoodDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-7414-6123 Pedram HeidariDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-6383-465X Funding
Granzyme B PET imaging as a marker of inflammatory bowel disease activityR01DK123143 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MAHMOOD, UMAR · 2020 to 2023
$2.3MCytotoxic lymphocyte function PET imaging to predict cancer immunotherapy responseR01CA214744 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI MAHMOOD, UMAR · 2017 to 2021
$1.9MEnhancing the therapeutic effect of receptor radionuclide therapy in neuroendocrine tumors by somatostatin receptor upregulationK08CA249047 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HEIDARI, PEDRAM · 2020 to 2024
$1.3MNCI NIH HHS K08 CA249047NIH HHS K08CA249047NIH HHS R01CA214744NIH HHS R01DK123143
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
CAR T-Cell therapygranzyme B PET imaginghumanized mouse modelmelanomaNSG mice
Identifiers
PMID41374439
PMCPMC12692077
What OpenQuestion holds
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