Evidence map›Paper›PMID 41374072›Full record

ArticleNutrients2025

Healthful and Unhealthful Plant-Based Diets and Their Association with Cardiometabolic Targets in Women Diagnosed with Breast Cancer: A Cross-Sectional Analysis of a Lifestyle Trial.

Sara Vitale, Elvira Palumbo, Angela D'Angelo, Matteo Di Maso, Jerry Polesel, Maria Grimaldi, Giuseppe Porciello, Assunta Luongo, Rosa Pica, Anna Crispo and 25 more

Abstract readMulticenter Study
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Sara VitaleEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Elvira PalumboEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0003-2844-2452
Angela D'AngeloDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Matteo Di MasoDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-6481-990X
Jerry PoleselUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.ORCID 0000-0001-9381-1520
Maria GrimaldiEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Giuseppe PorcielloEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-8731-2773
Assunta LuongoEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-1099-2686
Rosa PicaEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Anna CrispoEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-8455-3328
Ilaria CalabreseHealthcare Direction "A. Cardarelli" Hospital, 80131 Naples, Italy.ORCID 0000-0002-4222-4665
Luca FalzoneDepartment of Biomedical and Biotechnological Sciences, Oncologic, Clinical and General Pathology Section, University of Catania, 95124 Catania, Italy.ORCID 0000-0001-7349-6826
Michelino De LaurentiisDivision of Breast Medical Oncology, Department of Breast and Thoracic Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0001-9009-1572
Vincenzo Di LauroDivision of Breast Medical Oncology, Department of Breast and Thoracic Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-2124-7534
Daniela CiannielloDivision of Breast Medical Oncology, Department of Breast and Thoracic Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Ernesta CavalcantiLaboratory Medicine Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0001-6302-1579
Anita MinopoliLaboratory Medicine Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0001-5909-0547
Marco CuomoLaboratory Medicine Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Renato de FalcoLaboratory Medicine Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Guglielmo ThomasClinica Mediterranea, 80122 Naples, Italy.ORCID 0000-0003-1984-4732
Massimiliano D'AiutoBreast Unit, Ospedale di Boscotrecase, 80042 Boscotrecase, Italy.
Massimo RinaldoBreast Unit, Ospedale di Boscotrecase, 80042 Boscotrecase, Italy.
Samuele MassarutBreast Surgical Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.
Agostino SteffanImmunopathology and Cancer Biomarkers Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.ORCID 0000-0002-6320-3054
Francesca CatalanoBreast Unit, Cannizzaro Hospital, 95021 Catania, Italy.
Francesco FerraùBreast Unit, Ospedale San Vincenzo, 98039 Taormina, Italy.
Rosalba RosselloBreast Unit, Ospedale San Vincenzo, 98039 Taormina, Italy.
Francesco MessinaBreast Unit, Ospedale Evangelico Betania, 80147 Naples, Italy.
Vincenzo MontesarchioDivision of Medical Oncology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
David J A JenkinsDepartment of Nutritional Sciences and Medicine, Temerty, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.ORCID 0000-0003-1192-9571
Gabriele RiccardiDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.ORCID 0000-0003-4151-8298
Carlo La VecchiaDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-1441-897X
Massimo LibraDepartment of Biomedical and Biotechnological Sciences, Oncologic, Clinical and General Pathology Section, University of Catania, 95124 Catania, Italy.ORCID 0000-0002-7232-7737
Egidio CelentanoEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-3193-5699
Livia S A AugustinEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-6673-8281

Funding

Italian Ministry of Health PE-2013-02358099
6 · The paper itself

Abstract

backgroundPlant-based diets are recommended in guidelines for the prevention of cancer and cardiometabolic diseases, which remain major causes of death in breast cancer survivors (BCS). Since not all plant foods are healthy, we calculated the plant-based dietary index (PDI), healthy (hPDI) and unhealthy (uPDI), and their associations with cardiometabolic targets in BCS.

methodsBaseline dietary and cardiometabolic data were derived from 492 (median age 51, IQR 46-59) female BCS participating in a multicentric lifestyle trial conducted in Italy. Dietary data were collected with 7-day food records. PDI, hPDI, and uPDI were calculated by assigning positive scores to all plant foods, healthy plant foods or less healthy plant foods, respectively, as defined by the literature (scores ranged from 18 to 90). Using logistic or multinomial regression models, we estimated the odds ratios (OR) and the corresponding 95% confidence intervals (CI) between PDIs and cardiometabolic risk factors.

resultsThe OR of being obese (BMI ≥ 30 Kg/m

conclusionsMaintaining cardiometabolic risk factors within normal ranges is clinically relevant in BCS, and this may be more likely when a plant-based diet is consumed, especially if low in unhealthy plant foods.

Indexed as

Breast NeoplasmsCardiovascular DiseasesDiet, HealthyDiet, VegetarianCancer SurvivorsCardiometabolic Risk FactorsCross-Sectional StudiesDiet, Plant-BasedFemaleHumansItalyLife StyleMiddle AgedObesitybreast cancer survivorscardiometabolic risk factorsdietary fiberhealthy plant-based dietmacronutrientsmicronutrientsPDI

Identifiers

PMID41374072
PMCPMC12694399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.