Evidence map›Paper›PMID 41373959›Full record

ArticleNutrients2025

Yunjung Lee, Na-Kyoung Lee, Nayoung Kim, Yong-Min Choi, Haebom Kim, Hyun-Dong Paik, Eunju Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yunjung LeeDepartment of Food and Nutrition, Kyungnam University, Changwon 51767, Republic of Korea.ORCID 0000-0003-4726-4671
Na-Kyoung LeeDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea.
Nayoung KimDepartment of Food and Nutrition, Kyungnam University, Changwon 51767, Republic of Korea.
Yong-Min ChoiDaesang Wellife, Seoul 03130, Republic of Korea.ORCID 0000-0002-6434-4537
Haebom KimDaesang Wellife, Seoul 03130, Republic of Korea.
Hyun-Dong PaikDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-9891-7703
Eunju ParkDepartment of Food and Nutrition, Kyungnam University, Changwon 51767, Republic of Korea.ORCID 0000-0002-3462-6090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis research examined the anti-obesity potential of

methodsForty male mice were randomly assigned (

resultsLn4 supplementation significantly attenuated body weight gain, visceral fat accumulation, and dyslipidemia, while improving lipid metabolism and hormonal balance. The Ln4-9 group exhibited effects comparable to those of orlistat, indicating potent anti-obesity activity. Ln4 also reduced serum triglyceride and total cholesterol concentrations and improved lipid and hormone profiles. At the molecular level, Ln4 downregulated adipogenic and lipogenic regulators (PPARγ, SREBP1c, and C/EBPα) while upregulating genes involved in lipolysis and fatty acid oxidation (PPARα, CPT1, and ACO) in the liver and adipose tissue. These changes were accompanied by lower insulin and leptin levels and restored adiponectin concentrations.

conclusionsCollectively, the results demonstrate that

Indexed as

AdipogenesisDiet, High-FatLactiplantibacillus plantarumLipid MetabolismObesityProbioticsAdipose TissueAnimalsLiverMaleMiceMice, Inbred C57BLWeight Gainadipogenesishigh-fat dietLactiplantibacillus plantarumlipid metabolismobesity

Identifiers

PMID41373959
PMCPMC12694492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.