Evidence map›Paper›PMID 41373887›Full record

ArticleInternational journal of molecular sciences2025

Multi-Target Neuroprotective Effects of Flavonoid-Rich

Arik Dahan, Moria Oz, Ludmila Yarmolinsky, Alon Zahavi, Nitza Goldenberg-Cohen, Boris Khalfin, Shimon Ben-Shabat, Bat Chen R Lubin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arik DahanDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.ORCID 0000-0002-3498-3514
Moria OzDepartment of Molecular Biology, Faculty of Natural Sciences, Ariel University, Ariel 40700, Israel.
Ludmila YarmolinskyDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.ORCID 0009-0004-4962-4938
Alon ZahaviOphthalmology Department and Eye Research Laboratory, Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva 4941492, Israel.ORCID 0000-0002-9451-5253
Nitza Goldenberg-CohenDepartment of Ophthalmology, Bnai-Zion Medical Center, Haifa 3339419, Israel.ORCID 0000-0002-5648-1873
Boris KhalfinDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.ORCID 0000-0003-1695-6544
Shimon Ben-ShabatDepartment of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva 8410501, Israel.ORCID 0000-0001-7551-5488
Bat Chen R LubinDepartment of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 40700, Israel.

Funding

Israeli Ministry of Innovation, Science and Technology Grant No 97231
6 · The paper itself

Abstract

Oxidative-stress-induced neuronal injury is a major contributor to neurodegenerative diseases, underscoring the need for novel neuroprotective strategies. Natural products with antioxidant and mitochondrial-stabilizing properties are increasingly recognized as promising multi-target therapeutics.

Indexed as

AntioxidantsFicusFlavonoidsMitochondriaNeuroprotective AgentsPlant ExtractsRetinal Ganglion CellsAnimalsCell Line, TumorCell SurvivalHumansMaleMiceOxidative StressPlant LeavesAntioxidantsFlavonoidsNeuroprotective AgentsPlant ExtractsethnopharmacologyFicus benjaminaflavonoidsneuroprotectionoxidative stresstraditional Chinese medicine

Identifiers

PMID41373887
PMCPMC12692513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.