Evidence map›Paper›PMID 41373790›Full record

ArticleInternational journal of molecular sciences2025

Liproxstatin-1 Protects SH-SY5Y Cells by Inhibiting H

Tingting Yan, Feng Ding, Zhongyuan Fang, Yan Zhao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. IMD-1 Protects SH-SY5Y Cells Against HNeurochemical research · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tingting YanDepartment of Bioengineering, Harbin Institute of Technology, Weihai 264209, China.ORCID 0009-0002-9735-9513
Feng DingDepartment of Bioengineering, Harbin Institute of Technology, Weihai 264209, China.
Zhongyuan FangDepartment of Bioengineering, Harbin Institute of Technology, Weihai 264209, China.
Yan ZhaoDepartment of Bioengineering, Harbin Institute of Technology, Weihai 264209, China.

Funding

the Double First-class Disciplines Construction Fund Project from Harbin Institute of Technology at Weihai 2023SYLHY18the Natural Science Foundation of Shandong province ZR2019MH048the Natural Science Foundation of Shandong province ZR2022QC149
6 · The paper itself

Abstract

Oxidative stress is a critical factor in the pathogenesis of various neuronal disorders, causing cellular damage and mitochondrial dysfunction. This study aimed to explore the protective effects of liproxstatin-1 against H

Indexed as

ApoptosisHydrogen PeroxideMitophagyCell Line, TumorCell SurvivalHumansMembrane Potential, MitochondrialMitochondriaOxidative StressProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesHydrogen PeroxideProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesAKT/mTORapoptosisH2O2liproxstatin-1mitophagy

Identifiers

PMID41373790
PMCPMC12691964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.