Evidence map›Paper›PMID 41373746›Full record

ReviewInternational journal of molecular sciences2025

Predictive Analysis and Validation of Critical Missense SNPs of the

Anastasiia T Davletgildeeva, Timofey E Tyugashev, Viktoriia V Sagalakova, Mingxing Zhao, Nikita A Kuznetsov

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anastasiia T DavletgildeevaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4419-3954
Timofey E TyugashevInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-2539-2894
Viktoriia V SagalakovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Mingxing ZhaoDepartment of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.ORCID 0009-0005-6712-8206
Nikita A KuznetsovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4016-198X

Funding

Russian Ministry of Science and Higher Education 121031300041-4
6 · The paper itself

Abstract

Human DNA dioxygenase ABH2 is a key enzyme of the AlkB family of Fe(II)/α-ketoglutarate-dependent oxygenases, which is specialized in removing alkyl groups from damaged DNA bases in the cell nucleus. At the same time, the occurrence of single-nucleotide polymorphisms (SNPs) in the human

Indexed as

AlkB Homolog 2, Alpha-Ketoglutarate-Dependent DioxygenaseMutation, MissensePolymorphism, Single NucleotideAmino Acid SubstitutionCatalytic DomainComputational BiologyDioxygenasesHumansIronALKBH2 protein, humanAlkB Homolog 2, Alpha-Ketoglutarate-Dependent DioxygenaseDioxygenasesIronbase methylationdemethylation efficiencyDNA repairenzymatic activityhuman DNA dioxygenase ABH2single-nucleotide polymorphism

Identifiers

PMID41373746
PMCPMC12692101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.