Evidence map›Paper›PMID 41373694›Full record

ArticleInternational journal of molecular sciences2025

Synthesis of 1,3-Thiazine and 1,4-Thiazepine Derivatives via Cycloadditions and Ring Expansion.

Márta Palkó, Nóra Becker, Edit Wéber, Matti Haukka, Attila Márió Remete

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Márta PalkóInstitute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0002-8265-7377
Nóra BeckerInstitute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Edit WéberDepartment of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Matti HaukkaDepartment of Chemistry, University of Jyväskylä, FIN-40014 Jyväskylä, Finland.ORCID 0000-0002-6744-7208
Attila Márió RemeteInstitute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.

Funding

Hungarian Research Foundation OTKA No. K-138871Ministry of Human Capacities TKP-2021-EGA-32
6 · The paper itself

Abstract

Non-cephem drugs with 1,3-thiazine-derived rings are very rare, although a number of bioactive 1,3-thiazine derivatives are known. Similarly, 1,4-thiazepine-derived drugs are rare, but many 1,4-thiazepine derivatives show interesting biological activities. Therefore, our aim was the synthesis of such

Indexed as

Heterocyclic CompoundsThiazepinesThiazinesCycloaddition ReactionStereoisomerismHeterocyclic CompoundsThiazepinesThiazines1,3-thiazines1,4-thiazepinesalkenescycloadditionhetero-Diels–Alder reactionβ-lactams

Identifiers

PMID41373694
PMCPMC12692644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.